Helicobacter pylori Infection: Current Status and Future Prospects on Diagnostic, Therapeutic and Control Challenges

A Elbehiry, E Marzouk, M Aldubaib, A Abalkhail… - Antibiotics, 2023 - mdpi.com
Helicobacter pylori (H. pylori) infection, which affects approximately half of the world's
population, remains a serious public health problem. As H. pylori infection leads to a number …

Helicobacter pylori Virulence Factors—Mechanisms of Bacterial Pathogenicity in the Gastric Microenvironment

J Baj, A Forma, M Sitarz, P Portincasa, G Garruti… - Cells, 2020 - mdpi.com
Gastric cancer constitutes one of the most prevalent malignancies in both sexes; it is
currently the fourth major cause of cancer-related deaths worldwide. The pathogenesis of …

Helicobacter pylori: an up-to-date overview on the virulence and pathogenesis mechanisms

HC Sharndama, IE Mba - Brazilian Journal of Microbiology, 2022 - Springer
Helicobacter pylori is an organism associated with ulcer disease and gastric cancer. The
latter is one of the most prevalent malignancies and currently the fourth major cause of …

Toll-like receptor-guided therapeutic intervention of human cancers: molecular and immunological perspectives

S Mukherjee, R Patra, P Behzadi, A Masotti… - Frontiers in …, 2023 - frontiersin.org
Toll-like receptors (TLRs) serve as the body's first line of defense, recognizing both
pathogen-expressed molecules and host-derived molecules released from damaged or …

Mechanisms of the Epithelial–Mesenchymal Transition and Tumor Microenvironment in Helicobacter pylori-Induced Gastric Cancer

J Baj, I Korona-Głowniak, A Forma, A Maani, E Sitarz… - Cells, 2020 - mdpi.com
Helicobacter pylori (H. pylori) is one of the most common human pathogens, affecting half of
the world's population. Approximately 20% of the infected patients develop gastric ulcers or …

Updated epidemiology of gastric cancer in Asia: Decreased incidence but still a big challenge

WS Shin, F Xie, B Chen, P Yu, J Yu, KF To, W Kang - Cancers, 2023 - mdpi.com
Simple Summary Gastric cancer (GC) is regarded as one of the most perilous malignancies
globally, with over one billion new cases and seven hundred and eighty-three thousand …

Helicobacter pylori‐related risk predictors of gastric cancer: The latest models, challenges, and future prospects

SZ Bakhti, S Latifi‐Navid, R Safaralizadeh - Cancer medicine, 2020 - Wiley Online Library
Helicobacter pylori is known as an important determinant of preneoplastic lesions or gastric
cancer (GC) risk. The bacterial genotypes may determine the clinical outcomes. However …

Advances in diagnosis of Helicobacter pylori through biosensors: Point of care devices

K Saxena, N Chauhan, U Jain - Analytical Biochemistry, 2021 - Elsevier
Invasive as well as non-invasive conventional techniques for the detection of Helicobacter
pylori (H. pylori) have several limitations that are being overcome by the development of …

Inhibition or reversal of the epithelial-mesenchymal transition in gastric cancer: pharmacological approaches

J Kozak, A Forma, M Czeczelewski, P Kozyra… - International journal of …, 2020 - mdpi.com
Epithelial-mesenchymal transition (EMT) constitutes one of the hallmarks of carcinogenesis
consisting in the re-differentiation of the epithelial cells into mesenchymal ones changing the …

Enrichment of CLDN18ARHGAP fusion gene in gastric cancers in young adults

I Nakayama, E Shinozaki, S Sakata… - Cancer …, 2019 - Wiley Online Library
Gastric cancer in young adults has been pointed out to comprise a subgroup associated with
distinctive clinicopathological features, including an equal gender distribution, advanced …