A One Health approach to the epidemiology, management, surveillance, and control of
leptospirosis relies on accessible and accurate diagnostics that can be applied to humans …

Background Acute undifferentiated febrile illness (AUFI) is caused by a multitude of diverse
pathogens, with significant morbidity and mortality in the developing world. The objective of …

Background The knowledge that persistent human papillomavirus (HPV) infection is the
main cause of cervical cancer has resulted in the development of prophylactic vaccines to …

C reactive protein (CRP), a marker for the presence of an inflammatory process, is the most
extensively studied marker for distinguishing bacterial from non-bacterial infections in febrile …

Summary Background In southeast Asia, antibiotic prescription in febrile patients attending
primary care is common, and a probable contributor to the high burden of antimicrobial …

Background Dengue infection can cause a wide spectrum of clinical outcomes. The severe
clinical manifestations occur sufficiently late in the disease course, during day 4–6 of illness …

Background Scrub typhus is a major cause of acute febrile illness in the tropics and is
endemic over large areas of the Asia Pacific region. The national and global burden of scrub …

Group B streptococcus, found in the vagina or lower gastrointestinal tract of about 10–40%
of women of reproductive age, is a leading cause of early life invasive bacterial disease …

Background Neglected tropical diseases (NTDs) affect most impoverished communities in
developing countries, like Myanmar in Southeast Asia. NTDs have been understudied and …

Background Scrub typhus is a neglected tropical disease that causes acute febrile illness.
Diagnosis is made based upon serology, or detection of the causative agent–Orientia …