Targeted drug delivery to the colon offers a myriad of benefits, including treatment of local
diseases, direct access to unique therapeutic targets and the potential for increasing …

The last twenty years of seminal microbiome research has uncovered microbiota's intrinsic
relationship with human health. Studies elucidating the relationship between an unbalanced …

Dietary prebiotics can be metabolized by different colonic microorganisms and release
several classes of metabolites, particularly SCFAs into the intestine lumen, influencing the …

Composition of the gut microbiota changes during ageing, but questions remain about
whether age is also associated with deficits in microbiome function and whether these …

A virus minimally contains a nucleic acid genome packaged by a protein coat. The genome
and capsid together are known as the nucleocapsid, which has an envelope containing a …

Background: We explored the long-term effects of cART on markers of gut damage,
microbial translocation, and paired gut/blood microbiota composition, with a focus on the …

Human immunodeficiency virus type 1 (HIV-1) infection of CD4+ T cells in the gut plays an
insidious role in acquired immunodeficiency syndrome (AIDS) pathogenesis. Host immune …

HIV-1 replication in the gastrointestinal (GI) tract causes severe CD4+ T-cell depletion and
disruption of the protective epithelial barrier in the intestinal mucosa, causing microbial …

Although the microbiota has largely been associated with the pathogenesis of viral
infections, most studies using omics techniques are correlational and hypothesis …

Obesity has reached an epidemic level worldwide, and bariatric surgery (BS) has been
proven to be the most efficient therapy to reduce severe obesity-related comorbidities. Given …