Longer human lives have led to a global burden of late-life disease. However, some older
people experience little ill health, a trait that should be extended to the general population …

Introduction: Polypharmacy, defined as the use of multiple drugs or more than are medically
necessary, is a growing concern for older adults. MEDLINE and EMBASE databases were …

Introduction It is currently admitted that adverse drug reactions (ADRs) account for a great
burden of disease. Of particular concern are ADR-induced hospital admissions, particularly …

Although prescribed and over-the-counter medications may improve a wide range of health
problems, they also may cause or contribute to harm, especially in older adults. Current-day …

Adverse drug reactions (ADRs) are an important health issue. While prevalence and risk
factors associated with ADRs in the general adult population have been well documented …

Importance There is substantial uncertainty about optimal glycemic control in older adults
with type 2 diabetes mellitus. Observations Four large randomized clinical trials (RCTs) …

Background: Despite potential harm that can result from polypharmacy, real-world data on
polypharmacy in the setting of heart failure (HF) are limited. We sought to address this …

Heart failure (HF) is a quintessential geriatric cardiovascular condition, with more than 50%
of hospitalizations occurring in adults age 75 years or older. In older patients, HF is closely …

Objective: to identify and summarize studies examining both drug-drug interactions (DDI)
and adverse drug reactions (ADR) in older adults polymedicated. Methods: an integrative …

Objective: To derive findings from different studies done on drug related hospital admissions
and comprehensively express the incidence and preventability of drug related hospital …