Molecular functionality of cytochrome P450 4 (CYP4) genetic polymorphisms and their clinical implications
YB Jarrar, SJ Lee - International journal of molecular sciences, 2019 - mdpi.com
Enzymes in the cytochrome P450 4 (CYP4) family are involved in the metabolism of fatty
acids, xenobiotics, therapeutic drugs, and signaling molecules, including eicosanoids …
acids, xenobiotics, therapeutic drugs, and signaling molecules, including eicosanoids …
Prevalence of insulin resistance in the Hungarian general and Roma populations as defined by using data generated in a complex health (interview and examination) …
Data mainly from one-off surveys clearly show that the health of Roma, the largest ethnic
minority of Europe, is much worse than that of the general population. However, results from …
minority of Europe, is much worse than that of the general population. However, results from …
Comparative risk assessment for the development of cardiovascular diseases in the Hungarian general and Roma population
Cardiovascular diseases (CVDs) are the number one cause of death globally, and the early
identification of high risk is crucial to prevent the disease and to reduce healthcare costs …
identification of high risk is crucial to prevent the disease and to reduce healthcare costs …
The fatty acid omega hydroxylase genes (CYP4 family) in the progression of metabolic dysfunction-associated steatotic liver disease (MASLD): An RNA sequence …
C Leahy, N Osborne, L Shirota, P Rote, YK Lee… - Biochemical …, 2024 - Elsevier
Fatty acid omega hydroxylase P450s consist of enzymes that hydroxylate various chain-
length saturated and unsaturated fatty acids (FAs) and bioactive eicosanoid lipids. The …
length saturated and unsaturated fatty acids (FAs) and bioactive eicosanoid lipids. The …
The genetic risk for hypertension is lower among the Hungarian Roma population compared to the general population
Estimating the prevalence of cardiovascular diseases (CVDs) and risk factors among the
Roma population, the largest minority in Europe, and investigating the role of genetic or …
Roma population, the largest minority in Europe, and investigating the role of genetic or …
Low prevalence of spectacle use in the Hungarian Roma population indicates unmet health needs
The Roma population is the largest transnational ethnic minority group in Europe, often
facing socioeconomic inequalities and various health problems. In the present study, we …
facing socioeconomic inequalities and various health problems. In the present study, we …
Cytochrome P450 Family 4F2 and 4F11 Haplotype Mapping and Association with Hepatic Gene Expression and Vitamin K Hydroxylation Activity
AN Alade, KG Claw, MG McDonald… - ACS Pharmacology & …, 2024 - ACS Publications
This study evaluated the underlying mechanistic links between genetic variability in vitamin
K metabolic pathway genes (CYP4F2 and CYP4F11) and phylloquinone hydroxylation …
K metabolic pathway genes (CYP4F2 and CYP4F11) and phylloquinone hydroxylation …
Age and origin of the founder antithrombin Budapest 3 (p. Leu131Phe) mutation; its high prevalence in the Roma population and its association with cardiovascular …
Z Bereczky, R Gindele, S Fiatal, M Speker… - Frontiers in …, 2021 - frontiersin.org
Background: Antithrombin (AT) is one of the most important regulator of hemostasis. AT
Budapest 3 (ATBp3) is a prevalent type II heparin-binding site (IIHBS) deficiency due to …
Budapest 3 (ATBp3) is a prevalent type II heparin-binding site (IIHBS) deficiency due to …
The higher prevalence of venous thromboembolism in the Hungarian Roma population could be due to elevated genetic risk and stronger gene-environmental …
Background: Interactions between genetic and environmental risk factors (GxE) contribute to
an increased risk of venous thromboembolism (VTE). Understanding how these factors …
an increased risk of venous thromboembolism (VTE). Understanding how these factors …
Screening attendance disparities among Hungarian-speaking Roma and non-Roma women in central and eastern European countries
The Roma populations in Central and Eastern Europe are two to three times more likely to
have unmet health needs compared to non-Roma residents. The aim of the present study …
have unmet health needs compared to non-Roma residents. The aim of the present study …