Mixed-mode chromatographic stationary phases: recent advancements and its applications for high-performance liquid chromatography

L Zhang, Q Dai, X Qiao, C Yu, X Qin, H Yan - TrAC Trends in Analytical …, 2016 - Elsevier
Chromatographic stationary phase is the core of high-performance liquid chromatography
(HPLC) system. Thereinto, the development of novel stationary phases with high separation …

Click reactions: Recent trends in preparation of new sorbents and stationary phases for extraction and chromatographic applications

SN Ghamat, Z Talebpour, A Mehdi - TrAC Trends in Analytical Chemistry, 2019 - Elsevier
Click chemistry is an approach that uses efficient and reliable reactions to bind two
molecular building blocks and avoids the formation of byproducts. It has become …

Cholesterol stationary phase in the separation and identification of siRNA impurities by two-dimensional liquid chromatography-mass spectrometry

S Studzińska, F Li, M Szumski, B Buszewski… - International Journal of …, 2022 - mdpi.com
The aim of this research was to develop a simple and efficient ion-pair reagent-free
chromatographic method for the separation and qualitative determination of oligonucleotide …

Polybutylene terephthalate-based stationary phase for ion-pair-free reversed-phase liquid chromatography of small interfering RNA. Part 1: Direct coupling with mass …

F Li, S Chen, S Studzińska, M Lämmerhofer - Journal of Chromatography A, 2023 - Elsevier
Nowadays, ion-pairing reversed-phase liquid chromatography (IP-RPLC) is the dominating
generic method for the analysis of nucleic acid related compounds, such as antisense …

Mixed-mode chromatography characteristics of chiralpak ZWIX (+) and ZWIX (−) and elucidation of their chromatographic orthogonality for LC× LC application

S Bäurer, M Ferri, A Carotti, S Neubauer… - Analytica Chimica …, 2020 - Elsevier
Two-dimensional liquid chromatography requires orthogonal columns and/or separation
principles in the first and second separation dimension. It is sometimes not straightforward to …

Fragment-based design of zwitterionic, strong cation-and weak anion-exchange type mixed-mode liquid chromatography ligands and their chromatographic …

M Ferri, S Bäurer, A Carotti, M Wolter, B Alshaar… - … of Chromatography A, 2020 - Elsevier
The role of individual functional groups has been assessed with regard to surface charge
and chromatographic retention. Coatings were prepared from various fragments of the chiral …

Surface-crosslinked poly (3-mercaptopropyl) methylsiloxane-coatings on silica as new platform for low-bleed mass spectrometry-compatible functionalized stationary …

A Zimmermann, J Horak, A Sievers-Engler… - … of Chromatography A, 2016 - Elsevier
A thin functional film of poly (3-mercaptopropyl) methylsiloxane was coated onto vinyl-
modified silica particles (5 μm, 100 Å pore size) and chemically crosslinked to the surface …

Stable-bond polymeric reversed-phase/weak anion-exchange mixed-mode stationary phases obtained by simultaneous functionalization and crosslinking of a poly (3 …

S Bäurer, A Zimmermann, U Woiwode… - … of Chromatography a, 2019 - Elsevier
A polymeric reversed-phase/weak anion exchange (Poly-RP/WAX) mixed-mode stationary
phase has been prepared by coating of a poly (3-mercaptopropyl) methylsiloxane film on …

Preparation and evaluation of maltose modified polymer-silica composite based on cross-linked poly glycidyl methacrylate as high performance liquid …

Z Chu, L Zhang, W Zhang - Analytica Chimica Acta, 2018 - Elsevier
A new maltose modified polymer-silica composite was fabricated and applied as high
performance liquid chromatography (HPLC) stationary phase. The cross-linked poly glycidyl …

Preparation and evaluation of a hydrophilic interaction and cation-exchange chromatography stationary phase modified with 2-methacryloyloxyethyl …

C Xiong, J Yuan, Z Wang, S Wang, C Yuan… - … of Chromatography A, 2018 - Elsevier
In this work, 2-methacryloyloxyethyl phosphorylcholine (MPC) was used as a ligand to
prepare a novel mixed-mode chromatography (MMC) stationary phase by the thiol-ene click …