Global trends in hepatocellular carcinoma epidemiology: implications for screening, prevention and therapy

AG Singal, F Kanwal, JM Llovet - Nature reviews Clinical oncology, 2023 - nature.com
Hepatocellular carcinoma (HCC) mortality rates are increasing globally, and particularly in
the Western world. Cirrhosis remains the predominant risk factor for HCC. However …

Hepatocellular carcinoma surveillance—Utilization, barriers and the impact of changing aetiology

DQ Huang, AG Singal, F Kanwal… - Nature Reviews …, 2023 - nature.com
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide.
Surveillance for HCC is critical for early detection and treatment, but fewer than one-quarter …

AASLD practice guidance on prevention, diagnosis, and treatment of hepatocellular carcinoma

AG Singal, JM Llovet, M Yarchoan, N Mehta… - Hepatology, 2023 - journals.lww.com
This guidance document provides an updated approach to the prevention, diagnosis, and
treatment of hepatocellular carcinoma (HCC). The prior American Association for the Study …

[HTML][HTML] Hepatocellular carcinoma in 2021: an exhaustive update

CA Philips, S Rajesh, DC Nair, R Ahamed… - Cureus, 2021 - ncbi.nlm.nih.gov
Primary liver cancer is a challenging global health concern with an estimated more than a
million persons to be affected annually by the year 2025. The commonest type is …

Nonalcoholic fatty liver disease and hepatocellular carcinoma: Insights in epidemiology, pathogenesis, imaging, prevention and therapy

SA Polyzos, L Chrysavgis, ID Vachliotis… - Seminars in cancer …, 2023 - Elsevier
Hepatocellular carcinoma (HCC) is estimated to be the third leading cause of cancer-related
mortality and is characterized by low survival rates. Nonalcoholic fatty liver disease (NAFLD) …

Multicenter validation of abbreviated MRI for detecting early-stage hepatocellular carcinoma

T Yokoo, N Masaki, ND Parikh, BF Lane, Z Feng… - Radiology, 2023 - pubs.rsna.org
Background Abbreviated MRI is a proposed paradigm shift for hepatocellular carcinoma
(HCC) surveillance, but data on its performance are lacking for histopathologically confirmed …

[HTML][HTML] Overview of Asian clinical practice guidelines for the management of hepatocellular carcinoma: An Asian perspective comparison

Y Cho, BH Kim, JW Park - Clinical and Molecular Hepatology, 2023 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is highly prevalent and the third most common cause of
cancer-related death in Asia. In contrast to the West, the main etiology of HCC in many Asian …

The management of hepatocellular carcinoma. Current expert opinion and recommendations derived from the 24th ESMO/World Congress on Gastrointestinal Cancer …

M Ducreux, GK Abou-Alfa, T Bekaii-Saab, J Berlin… - ESMO open, 2023 - Elsevier
Highlights•The incidence of HCC will continue to rise.•HCC is curable at an early
stage.•New locoregional treatments such as radioembolisation are showing impressive …

Risk stratification and early detection biomarkers for precision HCC screening

YT Lee, N Fujiwara, JD Yang, Y Hoshida - Hepatology, 2023 - journals.lww.com
Hepatocellular carcinoma (HCC) mortality remains high primarily due to late diagnosis as a
consequence of failed early detection. Professional societies recommend semi‐annual HCC …

Rational HCC screening approaches for patients with NAFLD

AG Singal, HB El-Serag - Journal of Hepatology, 2022 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of developing
hepatocellular carcinoma (HCC), especially among those who have cirrhosis or advanced …