Endogenous circadian oscillators regulate molecular, cellular and physiological rhythms,
synchronizing tissues and organ function to coordinate activity and metabolism with …

Although sleep appears to be broadly conserved in animals, the physiological functions of
sleep remain unclear. In this study, we sought to identify a physiological defect common to a …

Sleep is a fundamental conserved physiological state across evolution, suggesting vital
biological functions that are yet to be fully clarified. However, our understanding of the …

Excess consumption of high-fat diet (HFD) is likely to result in obesity and increases the
predisposition to associated health disorders. Drosophila melanogaster has emerged as an …

Sleep restriction is associated with increased cardiovascular risk, which is more pronounced
in female than male persons. We reported recently first causal evidence that mild, prolonged …

Aims The current lifestyle trend has made people vulnerable to diabetes and related
diseases. Years of scientific research have not been able to yield a cure to the disease …

People are constantly exposed to phthalates, due to their common use in the production of
plastics, pharmaceuticals, cosmetics and skin care products. The ability of phthalates to …

抄録 Epidemiological and animal studies have demonstrated that ingestion of green tea
enhances healthy life. However, caffeine in green tea can interfere with sleep. In this report …

A key feature of circadian rhythms is the sleep/wake cycle. Sleep causes reduced
responsiveness to the environment, which puts animals in a particularly vulnerable state; yet …

Objective: Advanced age is associated with prominent impairment in allocentric navigation
dependent on the hippocampus. This study examined whether age-related impairment in …