Role of SARS-CoV-2 spike-protein-induced activation of microglia and mast cells in the pathogenesis of neuro-COVID

TC Theoharides, D Kempuraj - Cells, 2023 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus
disease 2019 (COVID-19). About 45% of COVID-19 patients experience several symptoms a …

Acute ischemic stroke and vaccine-induced immune thrombotic thrombocytopenia post COVID-19 vaccination; a systematic review

Z Kolahchi, MH Khanmirzaei, A Mowla - Journal of the neurological …, 2022 - Elsevier
Introduction One of the rare but potentially serious side effects of COVID-19 vaccination is
arterial and venous thrombosis. Acute ischemic stroke (AIS) cases have been reported post …

Mitochondrial dynamics in SARS-COV2 spike protein treated human microglia: implications for neuro-COVID

E Clough, J Inigo, D Chandra, L Chaves… - Journal of Neuroimmune …, 2021 - Springer
Emerging clinical data from the current COVID-19 pandemic suggests that~ 40% of COVID-
19 patients develop neurological symptoms attributed to viral encephalitis while in COVID …

[HTML][HTML] Post COVID-19 vaccination-associated neurological complications

SA Assiri, RMM Althaqafi, K Alswat… - Neuropsychiatric …, 2022 - ncbi.nlm.nih.gov
Post COVID-19 Vaccination-Associated Neurological Complications - PMC Back to Top Skip
to main content NIH NLM Logo Access keys NCBI Homepage MyNCBI Homepage Main …

The pandemic brain: Neuroinflammation in non-infected individuals during the COVID-19 pandemic

L Brusaferri, Z Alshelh, D Martins, M Kim… - Brain, behavior, and …, 2022 - Elsevier
While COVID-19 research has seen an explosion in the literature, the impact of pandemic-
related societal and lifestyle disruptions on brain health among the uninfected remains …

Brain fog: A narrative review of the most common mysterious cognitive disorder in COVID-19

M Aghajani Mir - Molecular Neurobiology, 2023 - Springer
It has been more than three years since COVID-19 impacted the lives of millions of people,
many of whom suffer from long-term effects known as long-haulers. Notwithstanding …

Exploring the immunogenic properties of SARS-CoV-2 structural proteins: PAMP: TLR signaling in the mediation of the neuroinflammatory and neurologic sequelae of …

MG Frank, M Fleshner, SF Maier - Brain, Behavior, and Immunity, 2023 - Elsevier
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) produces an array of
neurologic and neuropsychiatric symptoms in the acute and post-acute phase of infection …

Recombinant SARS-CoV-2 Spike Protein and its Receptor Binding Domain stimulate release of different pro-inflammatory mediators via activation of distinct receptors …

I Tsilioni, TC Theoharides - Molecular Neurobiology, 2023 - Springer
SARS-CoV-2 infects cells via its spike (S) protein binding to its surface receptor angiotensin
converting enzyme 2 (ACE2) on target cells and results in acute symptoms involving …

Psychological stress as a risk factor for accelerated cellular aging and cognitive decline: The involvement of microglia-neuron crosstalk

M Carrier, E Šimončičová, MK St-Pierre… - Frontiers in molecular …, 2021 - frontiersin.org
The relationship between the central nervous system (CNS) and microglia is lifelong.
Microglia originate in the embryonic yolk sac during development and populate the CNS …

NOX2 activation in COVID-19: Possible implications for neurodegenerative diseases

C Sindona, G Schepici, V Contestabile, P Bramanti… - Medicina, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19) is a rapidly spreading contagious infectious disease
caused by the pathogen severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …