Since 2006, several longitudinal studies have assessed environmental or behavioural
factors that seem to modify the risk of developing Parkinson's disease. Increased risk of …

Amyotrophic lateral sclerosis (ALS), also known as motor neuron disease, is characterized
by the degeneration of both upper and lower motor neurons, which leads to muscle …

In the 12 years since the publication of the first Consensus Paper of the WFSBP on
biomarkers of neurodegenerative dementias, enormous advancement has taken place in …

Although amyotrophic lateral sclerosis (ALS) was identified as a neurological condition 150
years ago, risk factors related to the onset and progression of ALS remain largely unknown …

Motor neuron disease can be viewed as an umbrella term describing a heterogeneous
group of conditions, all of which are relentlessly progressive and ultimately fatal. The …

As clinical evidence supports a negative impact of dysfunctional energy metabolism on the
disease progression in amyotrophic lateral sclerosis, it is vital to understand how the energy …

Oxidative stress has been reported to be involved in the onset and development of
amyotrophic lateral sclerosis (ALS). Data from clinical studies have highlighted increased …

The lack of biomarkers for early diagnosis, clinical stratification and to monitor treatment
response has hampered the development of new therapies for amyotrophic lateral sclerosis …

Sex differences in brain physiology and by inference various pathologies are generally
recognized, however frequently ignored in epidemiological and experimental studies …

Objective: To determine the associations between plasma creatinine (PCr), plasma uric acid
(PUA), and urinary oxidative stress (OS) biomarkers with the ALSFRS-R at baseline and …