The Role of Glutathione and Its Precursors in Type 2 Diabetes

D Tuell, G Ford, E Los, W Stone - Antioxidants, 2024 - mdpi.com
Type 2 diabetes (T2D) is a major worldwide health crisis affecting about 6.2% of the world's
population. Alarmingly, about one in five children in the USA have prediabetes. Glutathione …

Mechanism of the antidiabetic action of Nigella sativa and Thymoquinone: a review

A Shaukat, A Zaidi, H Anwar, N Kizilbash - Frontiers in Nutrition, 2023 - frontiersin.org
Introduction Long used in traditional medicine, Nigella sativa (NS; Ranunculaceae) has
shown significant efficacy as an adjuvant therapy for diabetes mellitus (DM) management by …

[HTML][HTML] The roles of glutathione and oxidative stress in diabetes and COVID-19

E Los, G Ford, D Tuell, D Macariola Jr, W Stone - Oxygen, 2024 - mdpi.com
Evidence suggests that COVID-19 infection increases the risk of type 1 (T1D) and type 2
diabetes (T2D). Diabetes, in turn, increases COVID-19 susceptibility and contributes to …

Propolis extract nanoparticles alleviate diabetes-induced reproductive dysfunction in male rats: antidiabetic, antioxidant, and steroidogenesis modulatory role

AB Emil, NH Hassan, S Ibrahim, EI Hassanen… - Scientific Reports, 2024 - nature.com
Diabetes can affect male fertility via oxidative stress and endocrine system disruption.
Nanomedicine based on natural products is employed to address diabetes complications …

[HTML][HTML] Physical exercise improved the hematological effect of vitamin D in type 2 diabetes mellitus-induced nephrotoxicity in rats

HA Abdulrahim, AF Odetayo, AT David… - … and Biophysics Reports, 2024 - Elsevier
Introduction Globally, one of the major causes of renal dysfunction is diabetes mellitus (DM),
and diabetic-induced nephrotoxicity has been linked with anemia. Presently, numerous …

[HTML][HTML] By-Products Valorization: Peptide Fractions from Milk Permeate Exert Antioxidant Activity in Cellular and In Vivo Models

V Scalcon, F Fiorese, M Albanesi, A Folda, G Betti… - Antioxidants, 2024 - mdpi.com
The discarding of agri-food by-products is a stringent problem due to their high
environmental impact. Recovery strategies can lead to a reduction of waste and result in …

[HTML][HTML] The Role of Antioxidant Plant Extracts' Composition and Encapsulation in Dietary Supplements and Gemmo-Derivatives, as Safe Adjuvants in Metabolic and …

BS Negreanu-Pirjol, T Negreanu-Pirjol, F Busuricu… - Pharmaceuticals, 2024 - mdpi.com
Given the current global circumstances, marked by severe environmental pollution—
including the contamination of food—along with daily stress and a sedentary lifestyle, many …

Challenging directions in pediatric diabetes-the place of oxidative stress and antioxidants in systemic decline

VV Lupu, I Miron, LM Trandafir, E Jechel… - Frontiers in …, 2024 - frontiersin.org
Diabetes is a complex condition with a rising global incidence, and its impact is equally
evident in pediatric practice. Regardless of whether we are dealing with type 1 or type 2 …

Exploration of novel DPP-IV inhibitory peptides from discarded eggshell membrane: An integrated in silico and in vitro study

L Zhu, Z Li, M Ma, X Huang, V Guyonnet, H Xiong - Food Bioscience, 2024 - Elsevier
Abstract Dipeptidyl peptidase-IV (DPP-IV) inhibitory peptides exhibit great potential to
alleviate type II diabetes. This study aimed to prepare, identify and explore the molecular …

[HTML][HTML] Pathological Role of High Sugar in Mitochondrial Respiratory Chain Defect-Augmented Mitochondrial Stress

ED Cham, TI Peng, MJ Jou - Biology, 2024 - mdpi.com
Simple Summary High glucose levels lead to the production of reactive oxygen species,
which, according to some research, is the link between high glucose and the toxicity …