Comprehensive review on tumour active palladium compounds and structure–activity relationships

MN Alam, F Huq - Coordination Chemistry Reviews, 2016 - Elsevier
This article provides a comprehensive review of palladium compounds that have been
evaluated for anticancer activity in vivo or in vitro from the era of discovery of cisplatin up to …

β-Lactoglobulin: An efficient nanocarrier for advanced delivery systems

Z Shafaei, B Ghalandari, A Vaseghi, A Divsalar… - … , Biology and Medicine, 2017 - Elsevier
Thanks to the progress of nanotechnology there are several agent-delivery systems that can
be selected to achieve rapid and specific delivery of a wide variety of biologically active …

A novel palladium (II) antitumor agent: Synthesis, characterization, DFT perspective, CT-DNA and BSA interaction studies via in-vitro and in-silico approaches

M Feizi-Dehnayebi, E Dehghanian… - … Acta Part A: Molecular …, 2021 - Elsevier
Since numerous people annually pass away due to cancer, research in this field is essential.
Thus a newly made and water like palladium (II) complex of formula [Pd (phen)(acac)] NO 3 …

DNA/BSA binding affinity studies of new Pd (II) complex with SS and NN donor mixed ligands via experimental insight and molecular simulation: Preliminary antitumor …

M Feizi-Dehnayebi, E Dehghanian… - Journal of Molecular …, 2021 - Elsevier
Due to the importance of metallo drugs that can bind to DNA and prohibit division of cancer
cells, a novel water-like palladium (II) complex,[Pd (phen)(proli-dtc)] NO 3 (phen= 1, 10 …

Synthesis and characterization of Pd (II) antitumor complex, DFT calculation and DNA/BSA binding insight through the combined experimental and theoretical aspects

M Feizi-Dehnayebi, E Dehghanian… - Journal of Molecular …, 2021 - Elsevier
A novel palladium (II) complex,[Pd (bpy)(acac)] NO 3 (where bpy and acac are 2, 2′-
bipyridine and acetylacetonato), has been synthesized and fully characterized through 1 H …

Spectroscopic and theoretical investigation of oxali–palladium interactions with β-lactoglobulin

B Ghalandari, A Divsalar, AA Saboury, T Haertlé… - … Acta Part A: Molecular …, 2014 - Elsevier
The possibility of using a small cheap dairy protein, β-lactoglobulin (β-LG), as a carrier for
oxali–palladium for drug delivery was studied. Their binding in an aqueous solution at two …

Palladium complexes: new candidates for anti-cancer drugs

EZ Jahromi, A Divsalar, AA Saboury… - Journal of the Iranian …, 2016 - Springer
Platinum complexes which are most studied metal complexes due to their importance as
adjuvant therapy of cancers aiming to induce tumor-cell-death. Some of the platinum-based …

Investigation on the interaction of newly designed anticancer Pd (II) complexes with different aliphatic tails and human serum albumin

A Divsalar, MJ Bagheri, AA Saboury… - The journal of …, 2009 - ACS Publications
The pharmacokinetics and pharmacodynamics of any drug will depend, largely, on the
interaction that it has with human serum albumin (HSA), the most abundant plasma protein …

Cannabidiol inhibits tau aggregation in vitro

S Alali, G Riazi, MR Ashrafi-Kooshk, S Meknatkhah… - Cells, 2021 - mdpi.com
A hallmark of Alzheimer's disease (AD) is the accumulation of tau protein in the brain.
Compelling evidence indicates that the presence of tau aggregates causes irreversible …

Anticancer activity, DNA-binding and DNA-denaturing aptitude of palladium (II) dithiocarbamates

MK Amir, SZ Khan, F Hayat, A Hassan, IS Butler - Inorganica Chimica Acta, 2016 - Elsevier
Although it is well known that cisplatin and its analogues are effective anticancer agents, but
their clinical use is restricted by some serious side effects. Palladium complexes are …