Therapeutic monoclonal antibodies in allergy: Targeting IgE, cytokine, and alarmin pathways
A Eggel, LF Pennington, TS Jardetzky - Immunological reviews, 2024 - Wiley Online Library
The etiology of allergy is closely linked to type 2 inflammatory responses ultimately leading
to the production of allergen‐specific immunoglobulin E (IgE), a key driver of many allergic …
to the production of allergen‐specific immunoglobulin E (IgE), a key driver of many allergic …
Contribution of T cell subsets to different food allergic diseases
L Hung, B Zientara, MC Berin - Immunological Reviews, 2024 - Wiley Online Library
Food allergies occur due to a lack of tolerance to the proteins found in foods. While IgE‐and
non‐IgE‐mediated food allergies have different clinical manifestations, epidemiology …
non‐IgE‐mediated food allergies have different clinical manifestations, epidemiology …
Type 2–polarized memory B cells hold allergen-specific IgE memory
Allergen-specific immunoglobulin E (IgE) antibodies mediate pathology in diseases such as
allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by …
allergic rhinitis and food allergy. Memory B cells (MBCs) contribute to circulating IgE by …
Irritable bowel syndrome: When food is a pain in the gut
H Hussein, S Van Remoortel… - Immunological …, 2024 - Wiley Online Library
Irritable bowel syndrome (IBS) is a chronic gastrointestinal condition associated with altered
bowel habits and recurrent abdominal pain, often triggered by food intake. Current …
bowel habits and recurrent abdominal pain, often triggered by food intake. Current …
Allergen‐specific B cell responses in oral immunotherapy‐induced desensitization, remission, and natural outgrowth in cow's milk allergy
Background Antigen‐specific memory B cells play a key role in the induction of
desensitization and remission to food allergens in oral immunotherapy and in the …
desensitization and remission to food allergens in oral immunotherapy and in the …
IgE in allergy: It takes two
IgE in allergy: It takes two | Science Translational Medicine news careers commentary
Journals Science Science brought to you byGoogle Indexer Log in journal-menu-img science …
Journals Science Science brought to you byGoogle Indexer Log in journal-menu-img science …
All roads lead to IgA: Mapping the many pathways of IgA induction in the gut
ER Siniscalco, A Williams… - Immunological …, 2024 - Wiley Online Library
The increasing prevalence of food allergy and related pathologies in recent years has
underscored the need to understand the factors affecting adverse reactions to food. Food …
underscored the need to understand the factors affecting adverse reactions to food. Food …
IgE versus IgG and IgA: Differential roles of allergen‐specific antibodies in sensitization, tolerization, and treatment of allergies
EF Knol, RJJ van Neerven - Immunological reviews, 2024 - Wiley Online Library
The prevalence of asthma, rhinitis, and food allergies has increased dramatically over the
last few decades. This increase originally started in western countries, but is now also …
last few decades. This increase originally started in western countries, but is now also …
Rocuronium-specific antibodies drive perioperative anaphylaxis but can also function as reversal agents in preclinical models
A Dejoux, Q Zhu, C Ganneau, ORL Goff… - Science Translational …, 2024 - science.org
Neuromuscular blocking agents (NMBAs) relax skeletal muscles to facilitate surgeries and
ease intubation but can lead to adverse reactions, including complications because of …
ease intubation but can lead to adverse reactions, including complications because of …
Whence and wherefore IgE?
RS Rahman, DR Wesemann - Immunological Reviews, 2024 - Wiley Online Library
Despite the near ubiquitous presence of Ig‐based antibodies in vertebrates, IgE is unique to
mammals. How and why it emerged remains mysterious. IgE expression is greatly …
mammals. How and why it emerged remains mysterious. IgE expression is greatly …