Although mortality rates from coronary heart disease in the western countries have declined
in the last few decades, morbidity caused by this disease is increasing and a substantial …

The Hemostatic System as a Modulator of Atherosclerosis | New England Journal of Medicine
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Background—Inflammatory reactions in coronary plaques play an important role in the
pathogenesis of acute atherothrombotic events; inflammation elsewhere is also associated …

Objective To compare the incidence of cardiovascular (CV) events in persons with
rheumatoid arthritis (RA) with that in people from the general population, adjusting for …

Platelets are central to inflammation-related manifestations of cardiovascular diseases
(CVD) such as atherosclerosis. Platelet-activating factor (PAF), thrombin, thromboxane A 2 …

The content of these European Society of Cardiology (ESC) Guidelines has been published
for personal and educational use only. No commercial use is authorized. No part of the ESC …

Background—Apoptotic microparticles are responsible for almost all tissue factor activity of
the plaque lipid core. We hypothesized that elevated levels of procoagulant microparticles …

Background—The specific role of apoptosis in human atherosclerosis remains unknown.
During apoptotic cell death, phosphatidylserine exposure on the cell surface confers a high …

Background—Low-molecular-weight heparins are attractive alternatives to unfractionated
heparin (UFH) for management of unstable angina/non–Q-wave myocardial infarction …

Hyperhomocysteinemia (HHcy) is an independent risk factor for cardiovascular disease,
including ischemic heart disease, stroke, and peripheral vascular disease. Mutations in the …