The inflamed brain in schizophrenia: the convergence of genetic and environmental risk factors that lead to uncontrolled neuroinflammation
Schizophrenia is a disorder with a heterogeneous etiology involving complex interplay
between genetic and environmental risk factors. The immune system is now known to play …
between genetic and environmental risk factors. The immune system is now known to play …
The entangled brain
L Pessoa - Journal of cognitive neuroscience, 2023 - direct.mit.edu
Abstract The Entangled Brain (Pessoa, L., 2002. MIT Press) promotes the idea that we need
to understand the brain as a complex, entangled system. Why does the complex systems …
to understand the brain as a complex, entangled system. Why does the complex systems …
A consensus protocol for functional connectivity analysis in the rat brain
J Grandjean, G Desrosiers-Gregoire, C Anckaerts… - Nature …, 2023 - nature.com
Task-free functional connectivity in animal models provides an experimental framework to
examine connectivity phenomena under controlled conditions and allows for comparisons …
examine connectivity phenomena under controlled conditions and allows for comparisons …
Unique spatiotemporal fMRI dynamics in the awake mouse brain
Human imaging studies have shown that spontaneous brain activity exhibits stereotypic
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …
spatiotemporal reorganization in awake, conscious conditions with respect to minimally …
Increased fMRI connectivity upon chemogenetic inhibition of the mouse prefrontal cortex
While shaped and constrained by axonal connections, fMRI-based functional connectivity
reorganizes in response to varying interareal input or pathological perturbations. However …
reorganizes in response to varying interareal input or pathological perturbations. However …
Evidence for increased parallel information transmission in human brain networks compared to macaques and male mice
A Griffa, M Mach, J Dedelley… - Nature …, 2023 - nature.com
Brain communication, defined as information transmission through white-matter
connections, is at the foundation of the brain's computational capacities that subtend almost …
connections, is at the foundation of the brain's computational capacities that subtend almost …
Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse
KY Choe, RAI Bethlehem, M Safrin, H Dong, E Salman… - Neuron, 2022 - cell.com
The neural basis of abnormal social behavior in autism spectrum disorders (ASDs) remains
incompletely understood. Here we used two complementary but independent brain-wide …
incompletely understood. Here we used two complementary but independent brain-wide …
Regional, layer, and cell-type-specific connectivity of the mouse default mode network
The evolutionarily conserved default mode network (DMN) is a distributed set of brain
regions coactivated during resting states that is vulnerable to brain disorders. How disease …
regions coactivated during resting states that is vulnerable to brain disorders. How disease …
Brain mapping across 16 autism mouse models reveals a spectrum of functional connectivity subtypes
Abstract Autism Spectrum Disorder (ASD) is characterized by substantial, yet highly
heterogeneous abnormalities in functional brain connectivity. However, the origin and …
heterogeneous abnormalities in functional brain connectivity. However, the origin and …
Chemogenetic stimulation of tonic locus coeruleus activity strengthens the default mode network
The default mode network (DMN) of the brain is functionally associated with a wide range of
behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron …
behaviors. In this study, we used functional magnetic resonance imaging (fMRI), positron …