Increasing evidence demonstrates that neuroplasticity, a fundamental mechanism of
neuronal adaptation, is disrupted in mood disorders and in animal models of stress. Here we …

Stress is a critical environmental trigger for the development of clinical depression, yet little
is known about the specific neurobiological mechanisms by which stress influences the …

The identification of key genes in transcriptomic data constitutes a huge challenge. Our
review of microarray reports revealed 88 genes whose transcription is consistently regulated …

Exposure to severe or persistent social stress may lead to the development of psychiatric
disorders such as anxiety and depression. These mood disorders are associated with …

The dentate gyrus (DG) of the hippocampus plays a crucial role in learning and memory.
This subregion is unique in its ability to generate new neurons throughout life and integrate …

Background: Expression of the neuronal membrane glycoprotein M6a (GPM6A), the
proteolipid protein (PLP/DM20) family member, is downregulated in the hippocampus of …

The aim of the present study was to identify potential biomarkers for depression in the
search for novel disease targets and treatment regimens. Furthermore, the study includes a …

Depressive disorders are among the most frequent forms of mental illness. Both genetic and
environmental factors, such as stress, are involved in the etiology of depression. Therefore …

The cellular and molecular mechanisms underlying neuropsychiatric and
neurodevelopmental disorders show that most of them can be categorized as …

Vi har fått stadig mer kunnskap om de alvorlige konsekvensene som dårlige oppvekstvilkår
kan ha for barn. I dag er det ikke lenger et spørsmål om oppvekstvilkår kan ha store negative …