One of the most powerful strategies to investigate biology we have as scientists, is the ability
to transfer genetic material in a controlled and deliberate manner between organisms. When …

Crucial prerequisites for the development of safe preclinical protocols in biomedical
research are suitable animal models that would allow for human‐related validation of …

The common marmoset (Callithrix jacchus) is increasingly attractive for use as a non-human
primate animal model in biomedical research. It has a relatively high reproduction rate for a …

3000 new references added since the first editionGives information necessary to produce
embryos totally through in vitro techniques Shows commercial applications of embryo and …

Coinjection of unfertilized mouse oocytes with sperm heads and exogenous DNA encoding
either a green fluorescent protein (GFP) or β-galactosidase reporter produced 64 to 94 …

Microinjection of DNA is now the most widespread method for generating transgenic
animals, but transgenesis rates achieved this way in higher mammals are extremely low. To …

Transgenic rhesus monkeys carrying the green fluorescent protein (GFP) gene were
produced by injecting pseudotyped replication-defective retroviral vector into the perivitelline …

The production of recombinant proteins is one of the major successes of biotechnology.
Animal cells are required to synthesize proteins with the appropriate post-translational …

Transgenic animals have been used for years to study gene function and to create models
for the study of human diseases. This approach has become still more justified after the …

Donor‐derived spermatogenesis after spermatogonial transplantation to recipient animals
could serve as a novel approach to manipulate the male germ line in species where current …