Manufacturers of insulin products for diabetes therapy have long sought ways to modify the
absorption rate of exogenously administered insulins in an effort to better reproduce the …

Insulin production by the pancreas follows a basic pattern where basal levels of insulin are
secreted during fasting periods, with prandial increases in insulin associated with food …

Importance Hypoglycemia, a serious risk for insulin-treated patients with type 2 diabetes,
negatively affects glycemic control. Objective To test whether treatment with basal insulin …

Aims/hypothesis A head-to-head randomised trial was conducted to evaluate
hypoglycaemia safety with insulin degludec 200 U/ml (degludec U200) and insulin glargine …

Aims To evaluate the efficacy and safety of ultra rapid lispro (URLi) versus lispro in adults
with type 1 diabetes in a 26‐week, treat‐to‐target, phase 3 trial. Materials and methods After …

Background Insulin degludec (degludec) is a second-generation basal insulin with an
improved pharmacokinetic–pharmacodynamic profile compared with first-generation basal …

OBJECTIVE To evaluate the efficacy and safety of ultra rapid lispro (URLi) versus lispro in
patients with type 2 diabetes on a basal-bolus insulin regimen. RESEARCH DESIGN AND …

The benefit of once-weekly basal insulin is less frequent dosing, which has the potential to
reduce the barrier to injection therapy and impact patient activation, adherence and …

The last 90 years have seen considerable advances in the management of type 1 and type 2
diabetes. Prof MacLean of Guy's Hospital wrote in the Postgraduate Medical Journal in 1926 …

Монография посвящена проблеме вариабельности гликемии при сахарном диабете.
Рассмотрены физиологические и патофизиологические основы флуктуаций уровня …