Treatment options for pancreatic neuroendocrine tumors

A Akirov, V Larouche, S Alshehri, SL Asa, S Ezzat - Cancers, 2019 - mdpi.com
The management of pancreatic neuroendocrine tumors (PanNETs) involves classification
into non-functional or functional PanNET, and as localized or metastatic PanNET. In …

CT-derived radiomic features to discriminate histologic characteristics of pancreatic neuroendocrine tumors

G Benedetti, M Mori, MM Panzeri, M Barbera… - La radiologia …, 2021 - Springer
Purpose To assess the ability of radiomic features (RF) extracted from contrast-enhanced CT
images (ceCT) and non-contrast-enhanced (non-ceCT) in discriminating histopathologic …

Pancreatic neuroendocrine neoplasms: the latest surgical and medical treatment strategies based on the current World Health Organization classification

H Ishida, AKY Lam - Critical Reviews in Oncology/Hematology, 2020 - Elsevier
There is a recent update in WHO classification of pancreatic neuroendocrine neoplasms
(PanNENs). Our aim is to analyse the latest management for patients with PanNENs …

Survival benefit of resection surgery for pancreatic ductal adenocarcinoma with liver metastases: a propensity score-matched SEER database analysis

TM Pausch, X Liu, J Cui, J Wei, Y Miao, U Heger… - Cancers, 2021 - mdpi.com
Simple Summary Pancreatic ductal adenocarcinoma is a devastating illness but guidelines
consider it unresectable once metastasized. However, resection of the primary tumor is …

The role of surgery for pancreatic neuroendocrine tumors

IA Ziogas, R Schmitz, D Moris, CJ Vatsaas - Anticancer Research, 2022 - ar.iiarjournals.org
Pancreatic neuroendocrine tumors (PNETs) arise from endocrine pancreatic cells and
comprise 3-5% of pancreatic cancers. Surgical resection is the only potentially curative …

[HTML][HTML] Risk factors, prognostic predictors, and nomograms for pancreatic cancer patients with initially diagnosed synchronous liver metastasis

BY Cao, F Tong, LT Zhang, YX Kang… - World Journal of …, 2023 - ncbi.nlm.nih.gov
BACKGROUND Liver metastasis (LM) remains a major cause of cancer-related death in
patients with pancreatic cancer (PC) and is associated with a poor prognosis. Therefore …

Cancer-associated fibroblasts induce proliferation and therapeutic resistance to everolimus in neuroendocrine tumors through Stat3 activation

T Amin, F Viol, J Krause, M Fahl, C Eggers… - …, 2023 - karger.com
Introduction: Cancer-associated fibroblasts (CAF) have been identified as relevant
contributors to cancer progression and drug resistance in many tumors. Although …

EMT molecular signatures of pancreatic neuroendocrine neoplasms

A Venugopal, A Michalczyk, M Khasraw… - International Journal of …, 2022 - mdpi.com
Neuroendocrine neoplasms (NENs) are relatively rare neoplasms occurring predominantly
in the gastrointestinal tract and pancreas. Their heterogeneity poses challenges for …

Efficacy and safety of 177Lu‑DOTATATE in patients with advanced pancreatic neuroendocrine tumours: data from the NETTER-R international, retrospective study

D Clement, S Navalkissoor, R Srirajaskanthan… - European journal of …, 2022 - Springer
Purpose NETTER-R aimed to determine the efficacy, safety and tolerability of 177Lu-
DOTATATE in patients with progressive, advanced pancreatic neuroendocrine tumours …

[HTML][HTML] Current update on imaging for pancreatic neuroendocrine neoplasms

N Segaran, C Devine, M Wang… - World Journal of Clinical …, 2021 - ncbi.nlm.nih.gov
Pancreatic neuroendocrine neoplasms (panNEN) are a heterogeneous group of tumors with
differing pathological, genetic, and clinical features. Based on clinical findings, they may be …