Cell-derived extracellular matrices (CD-ECMs) captured increasing attention since the first
studies in the 1980s. The biological resemblance of CD-ECMs to their in vivo counterparts …

The degradation of cartilage in the human body is impacted by aging, disease, genetic
predisposition and continued insults resulting from daily activity. The burden of cartilage …

The application of cell-derived extracellular matrix (ECM) in tissue engineering has gained
increasing interest because it can provide a naturally occurring, complex set of …

The extracellular matrix (ECM) is an intricate network of proteins that surrounds cells and
has a central role in establishing an environment that is conducive to tissue-specific cell …

Due to a blood supply shortage, articular cartilage has a limited capacity for self-healing
once damaged. Articular chondrocytes, cartilage progenitor cells, embryonic stem cells, and …

Significant research efforts have been undertaken in the last decade in the development of
stem cell-based therapies for cartilage repair. Among the various stem cell sources …

Articular cartilage is difficult to heal once injury or disease occurs. Autologous chondrocyte
transplantation is a biological treatment with good prognosis, but donor site morbidity and …

Bone implants for clinical application should be endowed with antibacterial activity,
biocompatibility, and even osteogenesis-promoting properties. In this work, metal–organic …

Background Intra-articular injection is indicated for mild or moderate osteoarthritis (OA).
However, the superiority of cell-based injection and the role of diverse cell sources are still …

Bone marrow mesenchymal stem cells (BMSC s) are an expandable population of stem
cells which can differentiate into osteoblasts, chondrocytes and adipocytes. Dysfunction of …