Neuroimaging genetics approaches to identify new biomarkers for the early diagnosis of autism spectrum disorder

S Nisar, M Haris - Molecular psychiatry, 2023 - nature.com
Autism-spectrum disorders (ASDs) are developmental disabilities that manifest in early
childhood and are characterized by qualitative abnormalities in social behaviors …

Glutamatergic neurotransmission: A potential pharmacotherapeutic target for the treatment of cognitive disorders

P Chakraborty, A Dey, AV Gopalakrishnan… - Ageing Research …, 2023 - Elsevier
In the mammalian brain, glutamate is regarded to be the primary excitatory neurotransmitter
due to its widespread distribution and wide range of metabolic functions. Glutamate plays …

Emerging signs of autism spectrum disorder in infancy: Putative neural substrate

M Hadders‐Algra - Developmental Medicine & Child Neurology, 2022 - Wiley Online Library
Autism spectrum disorder (ASD) is characterized by altered development of the social brain
with prominent atypical features in the fronto‐temporo‐parietal cortex and cerebellum. Early …

Increased glutamate and glutamine levels and their relationship to astrocytes and dopaminergic transmissions in the brains of adults with autism

M Oya, K Matsuoka, M Kubota, J Fujino, S Tei… - Scientific Reports, 2023 - nature.com
Increased excitatory neuronal tones have been implicated in autism, but its mechanism
remains elusive. The amplified glutamate signals may arise from enhanced glutamatergic …

[HTML][HTML] Pre-autism: What a paediatrician should know about early diagnosis of autism‎

M Al-Beltagi - World journal of clinical pediatrics, 2023 - ncbi.nlm.nih.gov
Autism, also known as an autism spectrum disorder, is a complex neurodevelopmental
disorder usually diagnosed in the first three years of a child's life. A range of symptoms …

Mutations associated with autism lead to similar synaptic and behavioral alterations in both sexes of male and female mouse brain

MK Tripathi, SK Ojha, M Kartawy, I Khaliulin… - Scientific Reports, 2024 - nature.com
Autism spectrum disorder (ASD) is a neurodevelopmental disorder based on synaptic
abnormalities. The estimated prevalence rate of male individuals diagnosed with ASD …

[HTML][HTML] Impact of pesticides exposure during neurodevelopmental period on autism spectrum disorders–A focus on gut microbiota

Y Yang, S Zhou, Y Xing, G Yang, M You - Ecotoxicology and environmental …, 2023 - Elsevier
Accumulating evidence indicates exposure to pesticides during the crucial
neurodevelopmental period increases susceptibility to many diseases, including the …

The state of the dopaminergic and glutamatergic systems in the valproic acid mouse model of autism spectrum disorder

A Maisterrena, E Matas, H Mirfendereski, A Balbous… - Biomolecules, 2022 - mdpi.com
Autism Spectrum Disorder (ASD) is a progressive neurodevelopmental disorder mainly
characterized by deficits in social communication and stereotyped behaviors and interests …

How oxidative stress induces depression?

N Ji, M Lei, Y Chen, S Tian, C Li, B Zhang - ASN neuro, 2023 - journals.sagepub.com
Depression increasingly affects a wide range and a large number of people worldwide, both
physically and psychologically, which makes it a social problem requiring prompt attention …

An overview on fecal profiles of amino acids and related amino-derived compounds in children with autism spectrum disorder in Tunisia

M Chamtouri, A Merghni, N Salazar, B Redruello… - Molecules, 2023 - mdpi.com
Autism spectrum disorder (ASD) is a neurodevelopmental pathology characterized by the
impairment of social interaction, difficulties in communication, and repetitive behaviors …