Regulation of membrane protein structure and function by their lipid nano-environment

I Levental, E Lyman - Nature Reviews Molecular Cell Biology, 2023 - nature.com
Transmembrane proteins comprise~ 30% of the mammalian proteome, mediating
metabolism, signalling, transport and many other functions required for cellular life. The …

Sphingolipids and lipid rafts: Novel concepts and methods of analysis

E Bieberich - Chemistry and physics of lipids, 2018 - Elsevier
About twenty years ago, the functional lipid raft model of the plasma membrane was
published. It took into account decades of research showing that cellular membranes are not …

Solubilization of membranes by detergents

A Helenius, KAI Simons - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1975 - Elsevier
30 membrane structure and function it is usually necessary to dissociate the membrane into
its components. The techniques for extraction and analysis of the membrane lipids are well …

Physical principles of membrane organization

JN Israelachvili, S Marčelja, RG Horn - Quarterly reviews of …, 1980 - cambridge.org
Membranes are the most common cellular structures in both plants and animals. They are
now recognized as being involved in almost all aspects of cellular activity ranging from …

Chemistry and metabolism of lipids in the vertebrate retina

AJ Fliesler, RE Anderson - Progress in lipid research, 1983 - Elsevier
80 SJ Fliesler and R E. Anderson stimulus (light) is well-defined and easily controlled.
Second, the stimulus is received by visual pigments which reside in specialized …

The modification of mammalian membrane polyunsaturated fatty acid composition in relation to membrane fluidity and function

CD Stubbs, AD Smith - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1984 - Elsevier
The earlier studies aimed at investigating the response of tissue fatty acyl composition to
variation in dietary fat were predominantly concerned with the state of essential fatty acid …

The description of membrane lipid conformation, order and dynamics by 2H-NMR

JH Davis - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1983 - Elsevier
The cell membrane is at the interface between the biological and physical sciences. The
eventual understanding of membrane biological function at the molecular level will be based …

Lipids of mitochondria

G Daum - Biochimica et Biophysica Acta (BBA)-Reviews on …, 1985 - Elsevier
The fluid mosaic membrane model of Singer and Nicolson [1] regards the arrangement of
phospholipids in biological membranes as a bilayer. Functional and structural proteins span …

[PDF][PDF] Structure and origin of ordered lipid domains in biological membranes

DA Brown, E London - The Journal of membrane biology, 1998 - academia.edu
The clearest function of membrane lipids is to form amphipathic bilayers that surround cells
and organelles and block leakage of hydrophilic compounds while housing membrane …

Influence of increased membrane cholesterol on membrane fluidity and cell function in human red blood cells

RA Cooper - Journal of supramolecular structure, 1978 - Wiley Online Library
Cholesterol and phospholipid are the two major lipids of the red cell membrane. Cholesterol
is insoluble in water but is solubilized by phospholipids both in membranes and in plasma …