Reading and Writing the Human Glycocode

N de Haan, MI Nielsen… - Annual Review of …, 2024 - annualreviews.org
The complex carbohydrate structures decorating human proteins and lipids, also called
glycans, are abundantly present at cell surfaces and in the secretome. Glycosylation is vital …

[HTML][HTML] Decrease in multiple complement proteins associated with development of islet autoimmunity and type 1 diabetes

BJM Webb-Robertson, ES Nakayasu, F Dong… - Iscience, 2024 - cell.com
Summary Type 1 diabetes (T1D) is a chronic condition caused by autoimmune destruction of
the insulin-producing pancreatic β cells. While it is known that gene-environment …

[HTML][HTML] N-glycosylation of serum proteins in adult type 1 diabetes mellitus exposes further changes compared to children at the disease onset

M Nemčić, M Tijardović, N Rudman, T Bulum… - Clinica chimica acta, 2023 - Elsevier
Objective Previously we have shown that plasma protein N-glycosylation is changed in
children at the onset of type 1 diabetes. In this study, we aim to identify N-glycan changes in …

Integrating Mendelian randomization and single-cell RNA sequencing to identify therapeutic targets of baicalin for type 2 diabetes mellitus

YC Liang, L Li, JL Liang, DL Liu, SF Chu… - Frontiers in …, 2024 - frontiersin.org
Background Alternative and complementary therapies play an imperative role in the clinical
management of Type 2 diabetes mellitus (T2DM), and exploring and utilizing natural …

Novel Protein Biomarkers and Therapeutic Targets for Type 1 Diabetes and Its Complications: Insights from Summary-Data-Based Mendelian Randomization and …

M Zou, J Yang - Pharmaceuticals, 2024 - mdpi.com
Millions of patients suffer from type 1 diabetes (T1D) and its associated complications.
Nevertheless, the pursuit of a cure for T1D has encountered significant challenges, with a …

Integrated serum proteomic and N‐glycoproteomic characterization of dengue patients

X Hu, J Song, G Ye, M Zhu, J Lan… - Journal of Medical …, 2024 - Wiley Online Library
Dengue fever is a mosquito‐borne viral disease caused by the dengue virus (DENV). It
poses a public health threat globally and, while most people with dengue have mild …

[HTML][HTML] The role of glycans in personalization of preventive health care

G Lauc, D Primorac - Croatian Medical Journal, 2024 - ncbi.nlm.nih.gov
More than 20 years have passed since the late Dr Allen Roses, then the worldwide vice-
president of genetics at GlaxoSmithKline, sent shockwaves through the medical community …

N GLIKOZILACIJA SERUMSKIH PROTEINA I IMUNOGLOBULINA AU ŠEĆERNOJ BOLESTI TIPA 1

M Nemčić - 2024 - repozitorij.unizg.hr
Sažetak N glikozilacij au šećernoj bolesti tipa 1 (ŠBT1) povezan a je s početkom bolesti,
dijabetičkim komplikacijama i lošom glikemijskom kontrolom, a osim navedenog, novija …

Visokoprotočna analiza N-glikozilacije komponente komplementa C3 kao biljega šećerne bolesti tipa 1

D Šoić - 2023 - dr.nsk.hr
Ubrzani razvoj analitičkih tehnika u posljednjih nekoliko desetljeća omogućio je temeljito
istraživanje procesa N-glikozilacije u brojnim patofioziološkim stanjima, a uočene promjene …