Abstract In this work, 13 thiosemicarbazones (1a–m) and 16 thiazoles (2a–p) were obtained,
which were properly characterized by spectroscopic and spectrometric techniques. The …

Leishmaniasis is an infectious disease complex caused by protozoa from the Leishmania
genus, which presents a broad spectrum of clinical manifestations: cutaneous …

Berberine chloride, a plant-derived isoquinoline alkaloid, has been demonstrated to have
leishmanicidal activity, which is mediated by generation of a redox imbalance and …

Toxicity and poor adherence to treatment that favors the generation of resistance in the
Leishmania parasites highlight the need to develop better alternatives. Here, we evaluated …

Isoxazole analogues derived from the neolignans veraguensin, grandisin, and machilin G
were previously synthesized with different substitution patterns through the bioisosterism …

Chalcone is a molecule with known biological activities. Based on this, a series of chalcone
derivatives bearing methyl, phenyl or furanyl substituents at different positions of A and B …

Sixteen 1, 4-diaryl-1, 2, 3-triazole compounds 4–19 derived from the tetrahydrofuran
neolignans veraguensin 1, grandisin 2, and machilin G 3 were tested against Leishmania …

Neglected diseases, such as Leishmaniasis, constitute a group of communicable diseases
that occur mainly in tropical countries. Considered a public health problem with limited …

Neglected tropical diseases are a diverse group of communicable pathologies that mainly
prevail in tropical and subtropical regions. Thus, the objective of this work was to evaluate …

Rotenone, isolated from Derris, Lonchocarpus, and Tephrosia from the family Fabaceae,
has been shown to have a variety of biological properties and is used in various agricultural …