The evolution of ovarian carcinoma subclassification

M Köbel, EY Kang - Cancers, 2022 - mdpi.com
Simple Summary Historically, cancers presenting with their main tumor mass in the ovary
have been classified as ovarian carcinomas (a concise term for epithelial ovarian cancer) …

Targeting the tumour microenvironment in platinum-resistant ovarian cancer

M Cummings, C Freer, NM Orsi - Seminars in cancer biology, 2021 - Elsevier
Ovarian cancer typically presents at an advanced stage, and although the majority of cases
initially respond well to platinum-based therapies, chemoresistance almost always occurs …

p53 and ovarian carcinoma survival: an Ovarian Tumor Tissue Analysis consortium study

M Köbel, EY Kang, A Weir, PF Rambau… - The Journal of …, 2023 - Wiley Online Library
Our objective was to test whether p53 expression status is associated with survival for
women diagnosed with the most common ovarian carcinoma histotypes (high‐grade serous …

Treatment strategies for ARID1A-deficient ovarian clear cell carcinoma

K Takahashi, M Takenaka, A Okamoto, DDL Bowtell… - Cancers, 2021 - mdpi.com
Simple Summary Deleterious mutations in SWI/SNF chromatin remodeling genes, such as
ARID1A, are present in more than 50% of cases of ovarian clear cell carcinoma (OCCC), a …

Integrated genomic/epigenomic analysis stratifies subtypes of clear cell ovarian carcinoma, highlighting their cellular origin

A Nishijima, K Oda, K Hasegawa, T Koso, K Asada… - Scientific Reports, 2024 - nature.com
The cellular origin of clear cell ovarian carcinoma (CCOC), a major histological subtype of
ovarian carcinoma remains elusive. Here, we explored the candidate cellular origin and …

Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma

FAM Saner, K Takahashi, T Budden… - Clinical Cancer …, 2024 - aacrjournals.org
Purpose: The purpose of this study was to evaluate RB1 expression and survival across
ovarian carcinoma histotypes and how co-occurrence of BRCA1 or BRCA2 (BRCA) …

Overexpression of IGF2BP3 as a potential oncogene in ovarian clear cell carcinoma

H Liu, Z Zeng, M Afsharpad, C Lin, S Wang… - Frontiers in …, 2020 - frontiersin.org
Ovarian Clear Cell Carcinoma (OCCC) displays distinctive clinical and molecular
characteristics and confers the worst prognosis among all ovarian carcinoma histotypes …

From clinical management to personalized medicine: novel therapeutic approaches for ovarian clear cell cancer

Z Liu, C Jing, F Kong - Journal of Ovarian Research, 2024 - Springer
Ovarian clear-cell cancer is a rare subtype of epithelial ovarian cancer with unique clinical
and biological features. Despite optimal cytoreductive surgery and platinum-based …

Preoperative serum microRNAs as potential prognostic biomarkers in ovarian clear cell carcinoma

K Suzuki, A Yokoi, K Yoshida, T Kato… - Journal of …, 2022 - pmc.ncbi.nlm.nih.gov
Objective Ovarian clear cell carcinoma (OCCC) is a subtype of epithelial ovarian carcinoma
with poor prognosis. However, no effective biomarkers have been established for predicting …

[PDF][PDF] Progression of Exosome-Mediated Chemotherapy Resistance in Cancer.

H Zhang, X Wang, Y Yu, Z Yang - Oncologie (Tech Science …, 2022 - cdn.techscience.cn
Chemotherapy plays an important role in controlling cancer progression, but the long-term
use of chemotherapeutic agents can lead to drug resistance and eventually treatment …