Mechanisms of synaptic transmission dysregulation in the prefrontal cortex: pathophysiological implications
The prefrontal cortex (PFC) serves as the chief executive officer of the brain, controlling the
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
highest level cognitive and emotional processes. Its local circuits among glutamatergic …
Circuit organization of the rodent medial prefrontal cortex
PG Anastasiades, AG Carter - Trends in neurosciences, 2021 - cell.com
The prefrontal cortex (PFC) orchestrates higher brain function and becomes disrupted in
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …
many mental health disorders. The rodent medial PFC (mPFC) possesses an enormous …
Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
DA Nation, MD Sweeney, A Montagne, AP Sagare… - Nature medicine, 2019 - nature.com
Vascular contributions to cognitive impairment are increasingly recognized,,,–as shown by
neuropathological,, neuroimaging,,,–, and cerebrospinal fluid biomarker, studies. Moreover …
neuropathological,, neuroimaging,,,–, and cerebrospinal fluid biomarker, studies. Moreover …
[PDF][PDF] Multi-sensory gamma stimulation ameliorates Alzheimer's-associated pathology and improves cognition
AJ Martorell, AL Paulson, HJ Suk, F Abdurrob… - Cell, 2019 - cell.com
We previously reported that inducing gamma oscillations with a non-invasive light flicker
(gamma entrainment using sensory stimulus or GENUS) impacted pathology in the visual …
(gamma entrainment using sensory stimulus or GENUS) impacted pathology in the visual …
The role of the medial prefrontal cortex in cognition, ageing and dementia
DD Jobson, Y Hase, AN Clarkson… - Brain …, 2021 - academic.oup.com
Humans require a plethora of higher cognitive skills to perform executive functions, such as
reasoning, planning, language and social interactions, which are regulated predominantly …
reasoning, planning, language and social interactions, which are regulated predominantly …
Optogenetics at the presynapse
Optogenetic actuators enable highly precise spatiotemporal interrogation of biological
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
processes at levels ranging from the subcellular to cells, circuits and behaving organisms …
Prefrontal–hippocampal interactions in episodic memory
H Eichenbaum - Nature Reviews Neuroscience, 2017 - nature.com
The roles of the hippocampus and prefrontal cortex (PFC) in memory processing—
individually or in concert—are a major topic of interest in memory research. These brain …
individually or in concert—are a major topic of interest in memory research. These brain …
What, if anything, is rodent prefrontal cortex?
Prefrontal cortex (PFC) means different things to different people. In recent years, there has
been a major increase in publications on the PFC, especially using mice. However …
been a major increase in publications on the PFC, especially using mice. However …
Integration of optogenetics with complementary methodologies in systems neuroscience
Modern optogenetics can be tuned to evoke activity that corresponds to naturally occurring
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …
local or global activity in timing, magnitude or individual-cell patterning. This outcome has …
The hippocampal sharp wave–ripple in memory retrieval for immediate use and consolidation
HR Joo, LM Frank - Nature Reviews Neuroscience, 2018 - nature.com
Various cognitive functions have long been known to require the hippocampus. Recently,
progress has been made in identifying the hippocampal neural activity patterns that …
progress has been made in identifying the hippocampal neural activity patterns that …