Fracture-related infection (FRI) remains a challenging complication that imposes a heavy
burden on orthopaedic trauma patients. The surgical management eradicates the local …

Behandlungen oberflächlicher Wundinfektionen mit lokalen Antibiotika werden wegen der
erhöhten Gefahr einer Resistenzentwicklung und fehlender Wirksamkeit in tieferen …

Three commercially available artificial bone substitutes with different compositions,
hydroxyapatite (HAp; Neobone®), carbonate apatite (CO3Ap; Cytrans®), and β-tricalcium …

Bone substitutes have been applied to treat osseous defects for a long time. To prevent
implant related infection (IRI) and enhance bone healing functionalized biomaterials …

Yes. Tissue concentrations of vancomycin and other antibiotics are significantly higher when
given via intraosseous regional administration for prophylaxis in total knee arthroplasty …

Background: Antibiotics delivered from implanted bone substitute materials (BSM) can
potentially be used to prevent acute infections and biofilm formation, providing high …

Limb salvage is widely practiced as standard of care in most cases of extremity bone
sarcoma. Allograft and endoprosthesis reconstructions are the most widely utilized …

Introduction: Bone implant related infection is still one of the biggest challenges in bone and
joint surgery. Antibiotic impregnated bone grafts seem to be promising in both treatment and …

Infections of bone are severe complications, and an optimization of grafting material with
antimicrobial drugs might be useful for prevention and treatment. This study aimed to …

В статье представлен обзор данных литературы об истории развития метода
лиофилизации аллогенных трансплантатов, применении лиофилизированных …