[HTML][HTML] Molecular pathogenesis of Cutaneous T cell Lymphoma: Role of chemokines, cytokines, and dysregulated signaling pathways

K Patil, S Kuttikrishnan, AQ Khan, F Ahmad… - Seminars in Cancer …, 2022 - Elsevier
Cutaneous T cell lymphomas (CTCLs) are a heterogeneous group of lymphoproliferative
neoplasms that exhibit a wide spectrum of immune-phenotypical, clinical, and …

Cellular interactions and inflammation in the pathogenesis of cutaneous T-cell lymphoma

V Stolearenco, MRJ Namini, SS Hasselager… - Frontiers in Cell and …, 2020 - frontiersin.org
Cutaneous T-cell lymphoma (CTCL) comprises a group of lymphoproliferative diseases
characterized by the accumulation of malignant T cells in chronically inflamed skin lesions …

Orchestral role of lipid metabolic reprogramming in T-cell malignancy

A Mehta, YK Ratre, VK Soni, D Shukla… - Frontiers in …, 2023 - frontiersin.org
The immune function of normal T cells partially depends on the maneuvering of lipid
metabolism through various stages and subsets. Interestingly, T-cell malignancies also …

Staphylococcus aureus alpha-toxin inhibits CD8+ T cell-mediated killing of cancer cells in cutaneous T-cell lymphoma

E Blümel, S Munir Ahmad, C Nastasi… - …, 2020 - Taylor & Francis
Staphylococcus aureus and its toxins have been linked to disease progression and mortality
in advanced stages of cutaneous T-cell lymphoma (CTCL). CD8+ T cells play a crucial role …

Pathogenesis of cutaneous T cell lymphoma: Involvement of Staphylococcus aureus

K Fujii - The Journal of Dermatology, 2022 - Wiley Online Library
Mycosis fungoides (MF) and Sézary syndrome (SS) are representative cutaneous
lymphomas. In their early stage, a small number of tumor cells and a large number of non …

Differential response of mycosis fungoides cells to vorinostat

ZA Bordeaux, SV Reddy, K Lee, W Lu, J Choi… - International journal of …, 2023 - mdpi.com
Mycosis fungoides (MF) is the most common form of cutaneous T-cell lymphoma (CTCL) and
is characterized by epidermotrophism of malignant CD4+ T-lymphocytes. When MF …

Gene expression profiling and immune cell-type deconvolution highlight robust disease progression and survival markers in multiple cohorts of CTCL patients

P Lefrançois, P Xie, L Wang, MT Tetzlaff… - …, 2018 - Taylor & Francis
ABSTRACT CTCL follows different courses depending on the clinical stage at the time of
diagnosis. Patients with early stage Mycosis Fungoides (MF) variant of CTCL may …

Safety and danger of biologic treatments in psoriasis in context of cutaneous T-cell lymphoma (CTCL)

K Kołkowski, M Sokołowska-Wojdyło - Advances in Dermatology and …, 2021 - termedia.pl
Microenvironment has a significant impact on the pathogenesis of cutaneous T-cell
lymphoma (CTCL), especially in the context of new emerging biologic therapies. Our aim …

[HTML][HTML] The Tumor Microenvironment as a Therapeutic Target in Cutaneous T Cell Lymphoma

LB Kwantwi, ST Rosen, C Querfeld - Cancers, 2024 - mdpi.com
Simple Summary Cutaneous T cell lymphomas (CTCLs) are a group of rare
lymphoproliferative malignancies manifesting in the skin. Cutaneous T cell lymphomas are …

Systemic chemotherapy promotes HIF‐1α‐mediated glycolysis and IL‐17F pathways in cutaneous T‐cell lymphoma

B Wang, K Li, H Wang, X Shen… - Experimental …, 2020 - Wiley Online Library
Background Systemic chemotherapy is often the last resort of advanced cutaneous T‐cell
lymphoma (CTCL). Tumor recurrence and adverse effects of systemic chemotherapy are the …