Mitochondrial permeability transition (mPT) is a phenomenon that abruptly causes the flux of
low molecular weight solutes (molecular weight up to 1,500) across the generally …

Ischemia-reperfusion (IR) injury is central to the pathology of major cardiovascular diseases,
such as stroke and myocardial infarction. IR injury is mediated by several factors including …

Major progress has been made in defining the basis of the mitochondrial permeability
transition, a Ca2+‐dependent permeability increase of the inner membrane that has puzzled …

Mitochondrial permeability transition pore (mPTP)-dependent cell death is a form of necrotic
cell death that is driven by mitochondrial dysfunction by the opening of the mPTP and is …

The mitochondrial permeability transition (PT) is a permeability increase of the inner
mitochondrial membrane mediated by a channel, the permeability transition pore (PTP) …

Cadmium is a widespread toxic pollutant of occupational and environmental concern
because of its diverse toxic effects: extremely protracted biological half-life (approximately …

The mitochondrial permeability transition (PT)–an abrupt increase permeability of the inner
membrane to solutes–is a causative event in ischemia–reperfusion injury of the heart, and …

Metastatic progression of cancer is associated with poor outcome, and here we examine
metabolic changes underlying this process. Although aerobic glycolysis is known to promote …

The mitochondrial permeability transition pore (MPTP) is a non-specific pore that opens in
the inner mitochondrial membrane (IMM) when matrix [Ca 2+] is high, especially when …

Thrombolytic therapy and revascularization strategies create a complete recanalization of
the occluded epicardial coronary artery in patients with myocardial infarction (MI). However …