Hepatocellular Carcinoma in Non-alcoholic Fatty Liver Disease: Emerging Burden

S Batool, K Morton Cuthrell, N Tzenios… - … Research Journal of …, 2022 - publish7promo.com
Liver is the largest solid organ in the body that performs over 100 functions. It removes the
toxins and waste products from the blood stream, maintains healthy blood sugar levels …

The unfolded protein response in immunity and inflammation

J Grootjans, A Kaser, RJ Kaufman… - Nature Reviews …, 2016 - nature.com
The unfolded protein response (UPR) is a highly conserved pathway that allows the cell to
manage endoplasmic reticulum (ER) stress that is imposed by the secretory demands …

[PDF][PDF] Gut microbiota profiling of pediatric nonalcoholic fatty liver disease and obese patients unveiled by an integrated meta‐omics‐based approach

F Del Chierico, V Nobili, P Vernocchi, A Russo… - …, 2017 - Wiley Online Library
There is evidence that nonalcoholic fatty liver disease (NAFLD) is affected by gut microbiota.
Therefore, we investigated its modifications in pediatric NAFLD patients using targeted …

[HTML][HTML] Non-alcoholic fatty liver disease and obesity: biochemical, metabolic and clinical presentations

S Milić, D Lulić, D Štimac - World journal of gastroenterology: WJG, 2014 - ncbi.nlm.nih.gov
Non-alcoholic fatty liver disease (NAFLD) is the most common liver disease in the world.
Presentation of the disease ranges from simple steatosis to non-alcoholic steatohepatitis …

[HTML][HTML] Roles of the peroxisome proliferator-activated receptors (PPARs) in the pathogenesis of nonalcoholic fatty liver disease (NAFLD)

YY Qiu, J Zhang, FY Zeng, YZ Zhu - Pharmacological Research, 2023 - Elsevier
Non-alcoholic fatty liver disease (NAFLD) encompasses a spectrum of disease phenotypes
which start with simple steatosis and lipid accumulation in the hepatocytes-a typical …

Probiotics may delay the progression of nonalcoholic fatty liver disease by restoring the gut microbiota structure and improving intestinal endotoxemia

L Xue, J He, N Gao, X Lu, M Li, X Wu, Z Liu, Y Jin… - Scientific Reports, 2017 - nature.com
Gut-derived bacterial lipopolysaccharide (LPS) and subsequent hepatic toll-like receptor 4
(TLR4) activation have been recognized to be involved in the onset of diet-induced …

Role of mitochondria in nonalcoholic fatty liver disease

F Nassir, JA Ibdah - International journal of molecular sciences, 2014 - mdpi.com
Nonalcoholic fatty liver disease (NAFLD) affects about 30% of the general population in the
United States and includes a spectrum of disease that includes simple steatosis, non …

[HTML][HTML] The role of iron and iron overload in chronic liver disease

S Milic, I Mikolasevic, L Orlic, E Devcic… - … medical journal of …, 2016 - ncbi.nlm.nih.gov
The liver plays a major role in iron homeostasis; thus, in patients with chronic liver disease,
iron regulation may be disturbed. Higher iron levels are present not only in patients with …

Global epidemiology of nonalcoholic fatty liver disease and perspectives on US minority populations

ZA Sherif, A Saeed, S Ghavimi, SM Nouraie… - Digestive diseases and …, 2016 - Springer
Background Non-alcoholic fatty liver disease (NAFLD) is a clinical syndrome predicted to be
the next global epidemic affecting millions of people worldwide. The natural course of this …

Obesity: An overview of possible role (s) of gut hormones, lipid sensing and gut microbiota

AK Mishra, V Dubey, AR Ghosh - Metabolism, 2016 - Elsevier
Obesity is one of the major challenges for public health in 21st century, with 1.9 billion
people being considered as overweight and 600 million as obese. There are certain …