Sex‐independent timing of the onset of central puberty revealed by nocturnal luteinizing hormone concentrations

A Demir, M Hero, A Juul, KM Main - Clinical Endocrinology, 2023 - Wiley Online Library
Objective We designed a longitudinal study to investigate the association between the ages
of central pubertal activation and the appearance of clinical signs of puberty and determined …

Quantification of overnight urinary gonadotropin excretion predicts imminent puberty in girls: a semi-longitudinal study

A Demir, A Büyükgebiz, A Aydin, M Hero - Hormones, 2024 - Springer
Purpose We explored the alternative of using overnight fold change in gonadotropin levels
by comparing the last-night-voided (LNV) and first-morning-voided (FMV) urine …

Identification of the LH surge by measuring intact and total immunoreactivity in urine for prediction of ovulation time

A Demir, M Hero, H Alfthan, A Passioni, JS Tapanainen… - Hormones, 2022 - Springer
Objectives In our earlier study, we separated three different molecular forms of urinary LH-ir
(U-LH-ir) by gel filtration and identified them by immunoassay in urine from regularly …

Quantification of urinary total luteinizing hormone immunoreactivity may improve the prediction of ovulation time

A Demir, M Hero, E Holopainen, A Juul - Frontiers in endocrinology, 2022 - frontiersin.org
Objectives Most of the currently available ovulation prediction kits provide a relatively rough
estimation of ovulation time with a short fertility window. This is due to their focus on the …

The negative impact of levothyroxine treatment on urinary luteinizing hormone measurements in pediatric patients with thyroid disease

A Demir, E Böber, S Darcan, A Aydın… - Frontiers in …, 2023 - frontiersin.org
Objectives Previous studies suggest urinary luteinizing hormone (LH) and follicle-stimulating
hormone (FSH) measurements by immunofluorometric assays (IFMA) as noninvasive …

Quantification of urinary gonadotropins by specific assays may improve the evaluation of sex‐specific hormonal changes in early infancy

A Demir, R Voutilainen, M Hero - Clinical Endocrinology, 2024 - Wiley Online Library
Objective The aim of this study was to investigate the feasibility of different gonadotropin
assays for determining total and intact luteinizing hormone (LH), and follicle‐stimulating …

Urine Sampling Protocol Recommendations for Reliable Determination of Total Urinary Luteinizing Hormone Immunoreactivity in the Pediatric Population

A Demir, A Aydin, A Büyükgebiz - Children, 2023 - mdpi.com
This study investigates day-to-day variations in urinary luteinizing hormone (U-LH)
concentrations in children, focusing on potential minimization or correction methods. 95 …

Quantification of urinary total luteinizing hormone immunoreactivity may improve the prediction of ovulation time

A Juul - … Preservation: From Next-generation Technologies to …, 2022 - books.google.com
Objectives: Most of the currently available ovulation prediction kits provide a relatively rough
estimation of ovulation time with a short fertility window. This is due to their focus on the …