[HTML][HTML] Overshadowed by the amygdala: the bed nucleus of the stria terminalis emerges as key to psychiatric disorders

MA Lebow, A Chen - Molecular psychiatry, 2016 - nature.com
The bed nucleus of the stria terminalis (BNST) is a center of integration for limbic information
and valence monitoring. The BNST, sometimes referred to as the extended amygdala, is …

Psychobiological mechanisms underlying the social buffering of the hypothalamic–pituitary–adrenocortical axis: A review of animal models and human studies across …

CE Hostinar, RM Sullivan, MR Gunnar - Psychological bulletin, 2014 - psycnet.apa.org
Discovering the stress-buffering effects of social relationships has been one of the major
findings in psychobiology in the last century. However, an understanding of the underlying …

[HTML][HTML] Oxytocin pathway gene networks in the human brain

DS Quintana, J Rokicki, D van der Meer… - Nature …, 2019 - nature.com
Oxytocin is a neuropeptide involved in animal and human reproductive and social behavior.
Three oxytocin signaling genes have been frequently implicated in human social behavior …

Galanin neurons in the medial preoptic area govern parental behaviour

Z Wu, AE Autry, JF Bergan, M Watabe-Uchida… - Nature, 2014 - nature.com
Mice display robust, stereotyped behaviours towards pups: virgin males typically attack
pups, whereas virgin females and sexually experienced males and females display parental …

[HTML][HTML] Marmosets: a neuroscientific model of human social behavior

CT Miller, WA Freiwald, DA Leopold, JF Mitchell… - Neuron, 2016 - cell.com
The common marmoset (Callithrix jacchus) has garnered interest recently as a powerful
model for the future of neuroscience research. Much of this excitement has centered on the …

A developmental, mentalization-based approach to the understanding and treatment of borderline personality disorder

P Fonagy, P Luyten - Development and psychopathology, 2009 - cambridge.org
The precise nature and etiopathogenesis of borderline personality disorder (BPD) continues
to elude researchers and clinicians. Yet, increasing evidence from various strands of …

Oxytocin: the great facilitator of life

HJ Lee, AH Macbeth, JH Pagani, WS Young 3rd - Progress in neurobiology, 2009 - Elsevier
Oxytocin (Oxt) is a nonapeptide hormone best known for its role in lactation and parturition.
Since 1906 when its uterine-contracting properties were described until 50 years later when …

Exploring the role of neuropeptides in depression and anxiety

T Rana, T Behl, A Sehgal, S Singh, N Sharma… - Progress in Neuro …, 2022 - Elsevier
Depression is one of the most prevalent forms of mental disorders and is the most common
cause of disability in the Western world. Besides, the harmful effects of stress-related mood …

Is target-based drug discovery efficient? Discovery and “off-target” mechanisms of all drugs

A Sadri - Journal of medicinal chemistry, 2023 - ACS Publications
Target-based drug discovery is the dominant paradigm of drug discovery; however, a
comprehensive evaluation of its real-world efficiency is lacking. Here, a manual systematic …

Vasopressin V1a and V1b receptors: from molecules to physiological systems

T Koshimizu, K Nakamura, N Egashira… - Physiological …, 2012 - journals.physiology.org
The neurohypophysial hormone arginine vasopressin (AVP) is essential for a wide range of
physiological functions, including water reabsorption, cardiovascular homeostasis, hormone …