High-confidence structural identification of metabolites relying on tandem mass spectrometry through isomeric identification: A tutorial
Y Song, Q Song, W Liu, J Li, P Tu - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
MS/MS currently serves as the workhorse for metabolomics. Structural identification is
extremely important to correlate statistical variables to biochemical functions and …
extremely important to correlate statistical variables to biochemical functions and …
Recent advances in high‐resolution traveling wave‐based ion mobility separations coupled to mass spectrometry
Recently, ion mobility spectrometry‐mass spectrometry (IMS‐MS) has become more readily
incorporated into various omics‐based workflows. These growing applications are due to …
incorporated into various omics‐based workflows. These growing applications are due to …
General method to obtain collision cross-section values in multipass high-resolution cyclic ion mobility separations
In recent years, ion mobility spectrometry-mass spectrometry (IMS-MS) has advanced the
field of omics-based research, especially with the development of high-resolution platforms; …
field of omics-based research, especially with the development of high-resolution platforms; …
Multistage ion mobility spectrometry combined with infrared spectroscopy for glycan analysis
The structural complexity of glycans makes their characterization challenging, not only
because of the presence of various isomeric forms of the precursor molecule but also …
because of the presence of various isomeric forms of the precursor molecule but also …
Probing High-Order Transient Oligomers Using Ion Mobility Mass Spectrometry Coupled with Infrared Action Spectroscopy
Understanding and controlling peptide aggregation are critical due to its neurotoxic
implications. However, structural information about the key intermediates, the oligomers, is …
implications. However, structural information about the key intermediates, the oligomers, is …
Enhancing the depth of analyses with next-generation ion mobility experiments
BP Zercher, TA Gozzo, AC Wageman… - Annual Review of …, 2023 - annualreviews.org
Recent developments in ion mobility (IM) technology have expanded the capability to
separate and characterize gas-phase ions of biomolecules, especially when paired with …
separate and characterize gas-phase ions of biomolecules, especially when paired with …
Strategy strengthens structural identification through hyphenating full collision energy ramp-MS2 and full exciting energy ramp-MS3 spectra: an application for …
K Zhang, H Li, J Shi, W Liu, Y Wang, P Tu, J Li… - Analytica Chimica …, 2024 - Elsevier
Abstract “MS/MS spectrum to structure” analysis is the most challenging task for MS/MS-
relied qualitative characterization. The conventional database-and computation-assisted …
relied qualitative characterization. The conventional database-and computation-assisted …
Ion Mobility Mass Spectrometry for Glycomics: Challenges and Opportunities When Met with Artificial Intelligence
Glycans possess complex and unique stereochemical features, endowing them with
distinguishing functions. An urgent need to develop a glycan sequencing method to …
distinguishing functions. An urgent need to develop a glycan sequencing method to …
An In Silico Infrared Spectral Library of Molecular Ions for Metabolite Identification
Infrared ion spectroscopy (IRIS) continues to see increasing use as an analytical tool for
small-molecule identification in conjunction with mass spectrometry (MS). The IR spectrum …
small-molecule identification in conjunction with mass spectrometry (MS). The IR spectrum …
Combining Liquid Chromatography and Cryogenic IR Spectroscopy in Real Time for the Analysis of Oligosaccharides
AH Abikhodr, S Warnke, A Ben Faleh… - Analytical …, 2024 - ACS Publications
While the combination of liquid chromatography (LC) and mass spectrometry (MS) serves as
a robust approach for oligosaccharide analysis, it has difficulty distinguishing the smallest …
a robust approach for oligosaccharide analysis, it has difficulty distinguishing the smallest …