[HTML][HTML] Hepatoprotective effects of rosmarinic acid: Insight into its mechanisms of action

TO Elufioye, S Habtemariam - Biomedicine & Pharmacotherapy, 2019 - Elsevier
Liver diseases such as hepatitis, fibrosis, cirrhosis, and hepatocellular carcinoma are one of
the major health challenges in the world and many conditions such as inadequate nutrition …

[HTML][HTML] Unraveling the beneficial effects of herbal Lebanese mixture “Za'atar”. History, studies, and properties of a potential healthy food ingredient

M Khalil, GR Caponio, F Diab, H Shanmugam… - Journal of Functional …, 2022 - Elsevier
Interest in plant-based food has grown in recent years due to their primary prevention
potential. Za'atar, an ancient and popular Lebanese herbal mixture, might disclose relevant …

A network pharmacology approach to investigating the mechanism of Tanshinone IIA for the treatment of liver fibrosis

MJ Shi, XL Yan, BS Dong, WN Yang, SB Su… - Journal of …, 2020 - Elsevier
Abstract Ethnopharmacological revelvance Tanshinone IIA (TIIA) is a major component
extracted from the traditional herbal medicine salvia miltiorrhiza (Danshen), which activates …

SIRT1/NFκB pathway mediates anti-inflammatory and anti-apoptotic effects of rosmarinic acid on in a mouse model of nonalcoholic steatohepatitis (NASH)

T Komeili-Movahhed, M Bassirian… - Journal of Receptors …, 2022 - Taylor & Francis
Nonalcoholic steatohepatitis (NASH) is considered as a common liver disease. SIRT1, a
pivotal sensor, controls activation of metabolic, inflammatory and apoptotic pathways …

Melatonin mitigates thioacetamide-induced hepatic fibrosis via antioxidant activity and modulation of proinflammatory cytokines and fibrogenic genes

MA Lebda, KM Sadek, TK Abouzed, HG Tohamy… - Life sciences, 2018 - Elsevier
Aims The potential antifibrotic effects of melatonin against induced hepatic fibrosis were
explored. Main methods Rats were allocated into four groups: placebo; thioacetamide …

[HTML][HTML] A comprehensive review of natural products against liver fibrosis: flavonoids, quinones, lignans, phenols, and acids

X Pan, X Ma, Y Jiang, J Wen, L Yang, D Chen… - Evidence-based …, 2020 - hindawi.com
Liver fibrosis resulting from continuous long-term hepatic damage represents a heavy
burden worldwide. Liver fibrosis is recognized as a complicated pathogenic mechanism with …

The phenylethanol glycoside liposome inhibits PDGF-induced HSC activation via regulation of the FAK/PI3K/Akt signaling pathway

SL Zhang, L Ma, J Zhao, SP You, XT Ma, XY Ye, T Liu - Molecules, 2019 - mdpi.com
Cistanche tubulosa is a traditional Chinese herbal medicine that is widely used to regulate
immunity, and phenylethanol glycosides (CPhGs) are among the primary components …

Protection of oxidative stress-induced DNA damage and apoptosis by rosmarinic acid in murine myoblast C2C12 cells

MJ Jeong, DS Lim, SO Kim, C Park, SH Leem… - Biotechnology and …, 2022 - Springer
Rosmarinic acid (RA) is a naturally occurring polyphenolic compound that has been applied
as a therapeutic antioxidant. However, its action mechanism in muscle cells remains …

Effectiveness of curcumin nanoparticles in rat liver fibrosis caused by thioacetamide

AM Radwan, SA Fatoh, A Massoud… - Environmental …, 2024 - Wiley Online Library
Although curcumin possesses anti‐inflammatory, antioxidant, and cytoprotective qualities, its
low absorption limits its medicinal uses. Before examining how curcumin influenced rats' …

The protective effects of rosmarinic acid on ethanol-induced gastritis in male rats: antioxidant defense enhancement

F Heidari, T Komeili-Movahhed… - Research in …, 2021 - journals.lww.com
Background and purpose: Gastritis is one of the most current gastrointestinal disorders
worldwide. Alcohol consumption is one of the major factors, which provides gastritis …