Temperature-responsive compounds as in situ gelling biomedical materials

HJ Moon, MH Park, MK Joo, B Jeong - Chemical Society Reviews, 2012 - pubs.rsc.org
Aqueous solutions that undergo sol-to-gel transition as the temperature increases have
been extensively studied during the last decade. The material can be designed by …

Biodegradable thermogels

MH Park, MK Joo, BG Choi, B Jeong - Accounts of chemical …, 2012 - ACS Publications
All living creatures respond to external stimuli. Similarly, some polymers undergo
conformational changes in response to changes in temperature, pH, magnetic field …

Untangling the evolution of Rab G proteins: implications of a comprehensive genomic analysis

TH Klöpper, N Kienle, D Fasshauer, S Munro - BMC biology, 2012 - Springer
Background Membrane-bound organelles are a defining feature of eukaryotic cells, and play
a central role in most of their fundamental processes. The Rab G proteins are the single …

Thousands of rab GTPases for the cell biologist

Y Diekmann, E Seixas, M Gouw… - PLoS computational …, 2011 - journals.plos.org
Rab proteins are small GTPases that act as essential regulators of vesicular trafficking. 44
subfamilies are known in humans, performing specific sets of functions at distinct subcellular …

An Overexpression Screen of Toxoplasma gondii Rab-GTPases Reveals Distinct Transport Routes to the Micronemes

K Kremer, D Kamin, E Rittweger, J Wilkes… - PLoS …, 2013 - journals.plos.org
The basic organisation of the endomembrane system is conserved in all eukaryotes and
comparative genome analyses provides compelling evidence that the endomembrane …

Sculpting the endomembrane system in deep time: high resolution phylogenetics of Rab GTPases

M Elias, A Brighouse… - Journal of cell …, 2012 - journals.biologists.com
The presence of a nucleus and other membrane-bounded intracellular compartments is the
defining feature of eukaryotic cells. Endosymbiosis accounts for the origins of mitochondria …

A cytoplasmic peptidoglycan amidase homologue controls mycobacterial cell wall synthesis

CC Boutte, CE Baer, K Papavinasasundaram, W Liu… - Elife, 2016 - elifesciences.org
Regulation of cell wall assembly is essential for bacterial survival and contributes to
pathogenesis and antibiotic tolerance in Mycobacterium tuberculosis (Mtb). However, little is …

Classifying the molecular functions of Rab GTPases in membrane trafficking using deep convolutional neural networks

QT Ho, YY Ou - Analytical biochemistry, 2018 - Elsevier
Deep learning has been increasingly used to solve a number of problems with state-of-the-
art performance in a wide variety of fields. In biology, deep learning can be applied to …

Trichomonas vaginalis pathobiology: new insights from the genome sequence

RP Hirt, N de Miguel, S Nakjang, D Dessi, YC Liu… - Advances in …, 2011 - Elsevier
The draft genome of the common sexually transmitted pathogen Trichomonas vaginalis
encodes one of the largest known proteome with 60,000 candidate proteins. This provides …

Unraveling the elusive rhoptry exocytic mechanism of Apicomplexa

D Sparvoli, M Lebrun - Trends in Parasitology, 2021 - cell.com
Apicomplexan parasites are unicellular eukaryotes that invade the cells in which they
proliferate. The development of genetic tools in Toxoplasma, and then in Plasmodium, in the …