LAMP-based point-of-care biosensors for rapid pathogen detection

D Das, CW Lin, HS Chuang - Biosensors, 2022 - mdpi.com
Seeking optimized infectious pathogen detection tools is of primary importance to lessen the
spread of infections, allowing prompt medical attention for the infected. Among nucleic-acid …

Principles and applications of loop-mediated isothermal amplification to point-of-care tests

JW Park - Biosensors, 2022 - mdpi.com
For the identification of nucleic acids, which are important biomarkers of pathogen-mediated
diseases and viruses, the gold standard for NA-based diagnostic applications is polymerase …

Electrochemical biosensor strategy combining DNA entropy-driven technology to activate CRISPR-Cas13a activity and triple-stranded nucleic acids to detect SARS …

C Zhuo, Z Song, J Cui, Y Gong, Q Tang, K Zhang… - Microchimica Acta, 2023 - Springer
By merging DNA entropy-driven technology with triple-stranded nucleic acids in an
electrochemical biosensor to detect the SARS-CoV-2 RdRp gene, we tackled the challenges …

Recent Trends and Innovations in Bead-Based Biosensors for Cancer Detection

HP Cheng, TH Yang, JC Wang, HS Chuang - Sensors, 2024 - mdpi.com
Demand is strong for sensitive, reliable, and cost-effective diagnostic tools for cancer
detection. Accordingly, bead-based biosensors have emerged in recent years as promising …

Needs, challenges and countermeasures of SARS-CoV-2 surveillance in cold-chain foods and packaging to prevent possible COVID-19 resurgence: a perspective …

Y Li, J Qiao, X Han, Z Zhao, J Kou, W Zhang, S Man… - Viruses, 2022 - mdpi.com
The pandemic caused by SARS-CoV-2 has a huge impact on the global economy. SARS-
CoV-2 could possibly and potentially be transmitted to humans through cold-chain foods …

On-chip screening of SARS-CoV-2 cDNA by LAMP-integrated rotational diffusometry

D Das, CW Lin, HS Chuang - Talanta, 2024 - Elsevier
The unprecedented pandemic has raised the demand for prompt, precise, and large-scale
virus detection techniques to control the transmission of contagious illnesses. In this study, a …

A systematic review of rapid SARS-CoV-2 detection methods for mitigating future outbreaks of emerging or historical pathogens

Y Wang, J Xiao, J Wei, Y Peng, M Li, Y Tong - Microchemical Journal, 2024 - Elsevier
In recent years, the widespread spread of many viruses among populations, eg, severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), monkeypox, and Middle East …

Integrated Sensing Chip for Ultrasensitive Label-Free Detection of the Products of Loop-Mediated Isothermal Amplification

S Mao, J Zhao, X Ding, VA Vuong, J Song, L Que - ACS sensors, 2023 - ACS Publications
Loop-mediated isothermal amplification (LAMP) is a nucleic acid amplification technique
that has been widely used for the detection of pathogens in many organisms. Current LAMP …