[HTML][HTML] Mitophagy and mitochondrial dynamics in type 2 diabetes mellitus treatment

Z Shan, WH Fa, CR Tian, CS Yuan, N Jie - Aging (Albany NY), 2022 - ncbi.nlm.nih.gov
The prevalence of type 2 diabetes is associated with inflammatory bowels diseases,
nonalcoholic steatohepatitis and even a spectrum of cancer such as colon cancer and liver …

Plumbagin exhibits genotoxicity and induces G2/M cell cycle arrest via ROS-mediated oxidative stress and activation of ATM-p53 signaling pathway in hepatocellular …

H Liu, W Zhang, L Jin, S Liu, L Liang, Y Wei - International journal of …, 2023 - mdpi.com
Plumbagin (5-hydroxy-2-methyl-1, 4-naphthoquinone, PLB), a naturally occurring
naphthoquinone mainly isolated from the plant Plumbago zeylanica L., has been proven to …

[HTML][HTML] Unravelling the potent anti-oxidant and anti-inflammatory actions of plumbagin: A review of preclinical discoveries

A Verma, A Goyal - Pharmacological Research-Modern Chinese Medicine, 2024 - Elsevier
Introduction Bioactive elements present in distinct medicinal plants and foods are appealing
molecules for the evolution of novel medications for the treatment of multiple illnesses linked …

Discovery of mitochondrion-targeting copper (ii)-plumbagin and-bipyridine complexes as chemodynamic therapy agents with enhanced antitumor activity

HQ Zhang, X Lu, JL Wu, MQ Ou, NF Chen… - Dalton …, 2024 - pubs.rsc.org
Four copper (II)-plumbagin and-bipyridine complexes (Cu1–Cu4) were synthesized as
chemodynamic therapy agents with enhanced antitumor activity. As lipophilic and positively …

Cucumeropsis mannii seed oil protects against Bisphenol A‐induced testicular mitochondrial damages

PM Aja, HA Ogwoni, PC Agu, EU Ekpono… - Food Science & …, 2023 - Wiley Online Library
There has been increasing search for the ameliorative properties of seed oils against
toxicants. bisphenol A acts as an estrogenic endocrine‐disrupting chemical capable of …

The phytochemical plumbagin: mechanism behind its “pleiotropic” nature and potential as an anticancer treatment

SS Panda, BK Biswal - Archives of Toxicology, 2024 - Springer
Chemotherapeutics are most often used to treat cancer, but side effects, drug resistance,
and toxicity often compromise their effectiveness. In contrast, phytocompound plumbagin …

Plant profile, phytochemistry, and ethnopharmacological uses of Swertia chirayita, Tribulus terrestris, and Plumbago zeylanica

A Al-Harrasi, S Bhatia, S Chigurupati… - Recent Advances in …, 2022 - taylorfrancis.com
Crude drugs have been used in the form of medicines since immemorial time in the form of
traditional Chinese medicine, Ayurveda, Kampo, traditional Korean medicine, and Unani …

Cucumeropsis mannii seed oil (CMSO) restores testicular mitochondrial dysfunctions by modulating the activities of dysregulated testicular mitochondrial enzymes in …

HA Ogwoni, PM Aja, ED Eze, PC Agu… - Food Science & …, 2024 - Wiley Online Library
Bisphenol A, a traditional endocrine disruptor, has been implicated in male infertility. This
study investigated the effect of Cucumeropsis mannii seed oil (CMSO) on bisphenol A (BPA) …

[图书][B] Recent Advances in Natural Products Science

A Al-Harrasi, S Bhatia, T Behl, MF Aldawsari… - 2022 - api.taylorfrancis.com
Advances in Natural Product science provides the summarized information related to global
herbal drug market and its regulations, ethnopharmacology of traditional crude drugs …

Protective effect of vitamin E against plumbagin-induced liver injury and oxidative stress: biochemical, redox, and mitochondrial permeability changes

OT Oyebode, IJ Bello, H Faleke, J Danisa… - Comparative Clinical …, 2023 - Springer
Plumbagin is a plant-based naphthoquinone with anti-cancer activity. However, its side
effects have limited its pharmacological significance. This study examined the effect of …