Mechanisms and disease consequences of nonalcoholic fatty liver disease

R Loomba, SL Friedman, GI Shulman - Cell, 2021 - cell.com
Nonalcoholic fatty liver disease (NAFLD) is the leading chronic liver disease worldwide. Its
more advanced subtype, nonalcoholic steatohepatitis (NASH), connotes progressive liver …

Update on prevention, diagnosis, and treatment of chronic hepatitis B: AASLD 2018 hepatitis B guidance

NA Terrault, ASF Lok, BJ McMahon, KM Chang… - …, 2018 - Wiley Online Library
This AASLD 2018 Hepatitis B Guidance is intended to complement the AASLD 2016
Practice Guidelines for Treatment of Chronic Hepatitis B (1) and update the previous …

The Asian Pacific Association for the Study of the Liver clinical practice guidelines for the diagnosis and management of metabolic associated fatty liver disease

M Eslam, SK Sarin, VWS Wong, JG Fan… - Hepatology …, 2020 - Springer
Metabolic associated fatty liver disease (MAFLD) is the principal worldwide cause of liver
disease and affects nearly a quarter of the global population. The objective of this work was …

Impact of the new definition of metabolic associated fatty liver disease on the epidemiology of the disease

VWS Wong, GLH Wong, J Woo, JM Abrigo… - Clinical …, 2021 - Elsevier
Background & Aims Recently, a group of hepatologists proposed to rename non-alcoholic
fatty liver disease (NAFLD) as metabolic associated fatty liver disease (MAFLD) with …

New trends on obesity and NAFLD in Asia

JG Fan, SU Kim, VWS Wong - Journal of hepatology, 2017 - Elsevier
Traditionally, obesity and its related diseases have been considered a problem in Western
countries. However, in the past two decades, urbanisation in many Asian countries has led …

Association of MAFLD with diabetes, chronic kidney disease, and cardiovascular disease: a 4.6-year cohort study in China

Y Liang, H Chen, Y Liu, X Hou, L Wei… - The Journal of …, 2022 - academic.oup.com
Context In 2020, the terminology of metabolic dysfunction–associated fatty liver disease
(MAFLD) was proposed to replace nonalcoholic fatty liver disease (NAFLD). Objectives This …

Geographical similarity and differences in the burden and genetic predisposition of NAFLD

TCF Yip, E Vilar‐Gomez, S Petta, Y Yilmaz… - Hepatology, 2023 - journals.lww.com
NAFLD has become a major public health problem for more than 2 decades with a growing
prevalence in parallel with the epidemic of obesity and type 2 diabetes (T2D). The disease …

Liver diseases and hepatocellular carcinoma in the Asia-Pacific region: burden, trends, challenges and future directions

LY Mak, K Liu, S Chirapongsathorn, KC Yew… - Nature Reviews …, 2024 - nature.com
Globally, nearly half of deaths from cirrhosis and chronic liver diseases (CLD) and three-
quarters of deaths from hepatocellular carcinoma (HCC) occur in the Asia-Pacific region …

Asian perspective on NAFLD-associated HCC

TCF Yip, HW Lee, WK Chan, GLH Wong… - Journal of hepatology, 2022 - Elsevier
Recent data suggest that non-alcoholic fatty liver disease (NAFLD) has become a major
public health problem in Asia, with an updated population prevalence of 34%. In parallel …

Diet-induced models of non-alcoholic fatty liver disease: food for thought on sugar, fat, and cholesterol

JM Eng, JL Estall - Cells, 2021 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) affects approximately 1 in 4 people worldwide and
is a major burden to health care systems. A major concern in NAFLD research is lack of …