T cells are crucial for immune functions to maintain health and prevent disease. T cell
development occurs in a stepwise process in the thymus and mainly generates CD4+ and …

T lymphocytes, the major effector cells in cellular immunity, produce cytokines in immune
responses to mediate inflammation and regulate other types of immune cells. Work in the …

The diabetic wound is easily to develop into a chronic wound because of the extremely
serious and complex inflammatory microenvironment including biofilm formation, over …

Follicular helper T (TFH) cells are a specialized subset of CD4+ T cells that essentially
support germinal center responses where high-affinity and long-lived humoral immunity is …

In recent times, metal oxide nanoparticles (NPs) have been regarded as having important
commercial utility. However, the potential toxicity of these nanomaterials has also been a …

Activated B cells participate in either extrafollicular (EF) or germinal center (GC) responses.
Canonical responses are composed of a short wave of plasmablasts (PBs) arising from EF …

Summary CD4 T follicular helper (TFH) cells support B cells, which are critical for germinal
center (GC) formation, but the importance of TFH-B cell interactions in cancer is unclear. We …

The immune system plays a critical role in protecting hosts from the invasion of organisms.
CD4 T cells, as a key component of the immune system, are central in orchestrating adaptive …

The discovery of CD4+ T cell subset–defining master transcription factors and framing of the
Th1/Th2 paradigm ignited the CD4+ T cell field. Advances in in vivo experimental systems …

Helping B cells and antibody responses is a major function of CD4+ T cells. It has been 10
years since the publication of Bcl6 as the lineage-defining transcription factor for T follicular …