Incorporating fatty liver disease in multidisciplinary care and novel clinical trial designs for patients with metabolic diseases

M Eslam, A Ahmed, JP Després, V Jha… - The Lancet …, 2021 - thelancet.com
With the global epidemics of obesity and associated conditions, including type 2 diabetes,
metabolic dysfunction-associated fatty liver disease, chronic kidney disease, hypertension …

Diet and exercise in NAFLD/NASH: beyond the obvious

G Semmler, C Datz, T Reiberger… - Liver International, 2021 - Wiley Online Library
Lifestyle represents the most relevant factor for non‐alcoholic fatty liver disease (NAFLD) as
the hepatic manifestation of the metabolic syndrome. Although a tremendous body of clinical …

Healthy lifestyle behaviors, mediating biomarkers, and risk of microvascular complications among individuals with type 2 diabetes: A cohort study

T Geng, K Zhu, Q Lu, Z Wan, X Chen, L Liu, A Pan… - PLoS …, 2023 - journals.plos.org
Background The influence of overall lifestyle behaviors on diabetic microvascular
complications remains unknown. In addition, the potential mediating biomarkers underlying …

Healthy lifestyle and life expectancy at age 30 years in the Chinese population: an observational study

Q Sun, D Yu, J Fan, C Yu, Y Guo, P Pei… - The Lancet Public …, 2022 - thelancet.com
Background The improvement of life expectancy is one of the aims of the Healthy China
2030 blueprint. We aimed to investigate the extent to which healthy lifestyles are associated …

Sleep, physical activity, sedentary behavior, and risk of incident dementia: a prospective cohort study of 431,924 UK Biobank participants

SY Huang, YZ Li, YR Zhang, YY Huang, BS Wu… - Molecular …, 2022 - nature.com
Although sleep, physical activity and sedentary behavior have been found to be associated
with dementia risk, findings are inconsistent and their joint relationship remains unclear. This …

Association of unhealthy lifestyle and childhood adversity with acceleration of aging among UK biobank participants

G Yang, X Cao, X Li, J Zhang, C Ma, N Zhang… - JAMA network …, 2022 - jamanetwork.com
Importance Accelerated aging makes adults more vulnerable to chronic diseases and death.
Whether childhood adversity is associated with accelerated aging processes, and to what …

Trends in the prevalence of cardiometabolic multimorbidity in the United States, 1999–2018

X Cheng, T Ma, F Ouyang, G Zhang, Y Bai - International journal of …, 2022 - mdpi.com
Cardiometabolic multimorbidity (co-existence of≥ 1 cardiometabolic diseases) is
increasingly common, while its prevalence in the US is unknown. We utilized data from 10 …

Association between healthy lifestyle and the occurrence of cardiometabolic multimorbidity in hypertensive patients: a prospective cohort study of UK Biobank

H Xie, J Li, X Zhu, J Li, J Yin, T Ma, Y Luo, L He… - Cardiovascular …, 2022 - Springer
Background Cardiometabolic multimorbidity (CMM) is becoming increasingly common in
patients with hypertension, and it is well established that healthy lifestyle plays a key role in …

Determinants and inequities in healthy working life expectancy in China

C Li, L Wang, L Ding, Y Zhou - Nature Medicine, 2024 - nature.com
Many countries are raising the pension age to mitigate the challenges of population aging,
but such a solution may ignore the disparities in health and working conditions across …

Metabolism and chronic inflammation: the links between chronic heart failure and comorbidities

Z Li, H Zhao, J Wang - Frontiers in Cardiovascular Medicine, 2021 - frontiersin.org
Heart failure (HF) patients often suffer from multiple comorbidities, such as diabetes, atrial
fibrillation, depression, chronic obstructive pulmonary disease, and chronic kidney disease …