The methylotrophic yeast Pichia pastoris (also known as Komagataella phaffii) is widely
used as a yeast cell factory for producing heterologous proteins. Recently, it has gained …

Komagataella phaffii (formerly known as Pichia pastoris) has become an increasingly
important microorganism for recombinant protein production. This yeast species has gained …

Chondroitin sulfate (CS) is widely applied in the medical, clinical, and nutraceutical fields.
However, all commercialized CS is extracted from animal tissues, which is associated with …

The promoter of the high-affinity glucose transporter Gth1 (P GTH1) is tightly repressed on
glucose and glycerol surplus, and strongly induced in glucose-limitation, thus enabling …

The current transition towards the circular bioeconomy requires a rational development of
biorefineries to sustainably fulfill the present demands. The use of Komagataella phaffii …

Bacillus licheniformis DW2 is an important industrial strain for bacitracin production, and it is
also used for biochemical production, however, the lack of effective toolkit for precise …

Flavor is an essential element of food quality. Flavor can be improved by adding flavoring
substances or via microbial fermentation to impart aroma. Aroma-producing yeasts are a …

Besides bakers' yeast, the methylotrophic yeast Komagataella phaffii (also known as Pichia
pastoris) has been developed into the most popular yeast cell factory for the production of …

Natural methylotrophs are attractive methanol utilization hosts, but lack flexible expression
tools. In this study, we developed yeast transcriptional device libraries for precise synthesis …

Background Ablynx NV, a subsidiary of Sanofi, has a long-standing focus on the
development of Nanobody® molecules as biopharmaceuticals (Nanobody® is a registered …