Emerging role of exosomes in cancer progression and tumor microenvironment remodeling

MDA Paskeh, M Entezari, S Mirzaei, A Zabolian… - Journal of hematology & …, 2022 - Springer
Cancer is one of the leading causes of death worldwide, and the factors responsible for its
progression need to be elucidated. Exosomes are structures with an average size of 100 nm …

Exosome processing and characterization approaches for research and technology development

JJ Lai, ZL Chau, SY Chen, JJ Hill… - Advanced …, 2022 - Wiley Online Library
Exosomes are extracellular vesicles that share components of their parent cells and are
attractive in biotechnology and biomedical research as potential disease biomarkers as well …

[HTML][HTML] Extracellular vesicles as drug delivery systems: Why and how?

OM Elsharkasy, JZ Nordin, DW Hagey… - Advanced drug delivery …, 2020 - Elsevier
Over the past decades, a multitude of synthetic drug delivery systems has been developed
and introduced to the market. However, applications of such systems are limited due to …

Oral administration of bovine milk-derived extracellular vesicles induces senescence in the primary tumor but accelerates cancer metastasis

M Samuel, P Fonseka, R Sanwlani, L Gangoda… - Nature …, 2021 - nature.com
The concept that extracellular vesicles (EVs) from the diet can be absorbed by the intestinal
tract of the consuming organism, be bioavailable in various organs, and in-turn exert …

Sustained Exosome‐Guided Macrophage Polarization Using Hydrolytically Degradable PEG Hydrogels for Cutaneous Wound Healing: Identification of Key Proteins …

G Kwak, J Cheng, H Kim, S Song, SJ Lee, Y Yang… - Small, 2022 - Wiley Online Library
Macrophages (Mφs) are characterized by remarkable plasticity, an essential component of
chronic inflammation. Thus, an appropriate and timely transition from proinflammatory (M1) …

The evolving landscape of exosomes in neurodegenerative diseases: exosomes characteristics and a promising role in early diagnosis

S Rastogi, V Sharma, PS Bharti, K Rani… - International journal of …, 2021 - mdpi.com
Neurodegenerative diseases (ND) remains to be one of the biggest burdens on healthcare
systems and serves as a leading cause of disability and death. Alzheimer's disease (AD) is …

MitoEVs: a new player in multiple disease pathology and treatment

X Zhou, S Liu, Y Lu, M Wan, J Cheng… - Journal of Extracellular …, 2023 - Wiley Online Library
Mitochondrial damage plays vital roles in the pathology of many diseases, such as cancers,
neurodegenerative diseases, aging, metabolic diseases and many types of organ injury …

Biogenesis, membrane trafficking, functions, and next generation nanotherapeutics medicine of extracellular vesicles

S Gurunathan, MH Kang, M Qasim… - International Journal of …, 2021 - Taylor & Francis
Extracellular vesicles (EVs) are a heterogeneous group of membrane-limited vesicles and
multi-signal messengers loaded with biomolecules. Exosomes and ectosomes are two …

Exosome-mediated stable epigenetic repression of HIV-1

S Shrivastava, RM Ray, L Holguin, L Echavarria… - Nature …, 2021 - nature.com
Abstract Human Immunodeficiency Virus (HIV-1) produces a persistent latent infection.
Control of HIV-1 using combination antiretroviral therapy (cART) comes at the cost of life …

RETRACTED: Exosomes Derived from miR-143-Overexpressing MSCs Inhibit Cell Migration and Invasion in Human Prostate Cancer by Downregulating TFF3

Y Che, X Shi, Y Shi, X Jiang, Q Ai, Y Shi, F Gong… - … Therapy-Nucleic Acids, 2019 - cell.com
Exosomes are membrane-enclosed nanovesicles that shuttle active cargoes, such as
mRNAs and microRNAs (miRNAs), between different cells. Mesenchymal stem cells (MSCs) …