BACKGROUND Although laboratory procedures, along with culture media formulations,
have improved over the past two decades, the issue remains that human IVF is performed in …

With the worldwide move towards single embryo transfer there has been a renewed focus
on the requirement for reliable means of assessing embryo viability. In an era of …

BACKGROUND The placenta is of utmost importance for intrauterine fetal development and
growth. Deregulation of placentation can lead to adverse outcomes for both mother and …

Bovine and ovine embryos exposed to a variety of unusual environments prior to the
blastocyst stage have resulted in the development of unusually large offspring which can …

This review considers how our understanding of preimplantation embryo metabolism has
progressed since the pioneering work on this topic in the late 1960s and early 1970s …

We describe a bovine embryo culture system that supports repeatable high development in
the presence of serum or BSA as well as under defined conditions in the absence of those …

Oocyte quality affects early embryonic survival, the establishment and maintenance of
pregnancy, fetal development, and even adult disease. Quality, or developmental …

Contents While much is known about the metabolism of exogenous nutrients such as
glucose, lactate, pyruvate, amino acids by oocytes and pre‐implantation mammalian …

Epidemiological studies have indicated that susceptibility of human adults to hypertension
and cardiovascular disease may result from intrauterine growth restriction and low birth …

BACKGROUND In animal models, in vitro culture of preimplantation embryos has been
shown to be a risk factor for abnormal fetal outcome, including high and low birthweight. In …