The relationship between gut microbiota and inflammatory diseases: the role of macrophages

J Wang, WD Chen, YD Wang - Frontiers in microbiology, 2020 - frontiersin.org
Gut microbiota, an integral part of the human body, comprise bacteria, fungi, archaea, and
protozoa. There is consensus that the disruption of the gut microbiota (termed “gut …

Chemokine-induced macrophage polarization in inflammatory conditions

P Ruytinx, P Proost, J Van Damme, S Struyf - Frontiers in immunology, 2018 - frontiersin.org
Macrophages represent a heterogeneous cell population and are known to display a
remarkable plasticity. In response to distinct micro-environmental stimuli, eg, tumor stroma …

[HTML][HTML] Monocyte and macrophage plasticity in tissue repair and regeneration

A Das, M Sinha, S Datta, M Abas, S Chaffee… - The American journal of …, 2015 - Elsevier
Heterogeneity and high versatility are the characteristic features of the cells of monocyte-
macrophage lineage. The mononuclear phagocyte system, derived from the bone marrow …

[HTML][HTML] Fate mapping reveals origins and dynamics of monocytes and tissue macrophages under homeostasis

S Yona, KW Kim, Y Wolf, A Mildner, D Varol, M Breker… - Immunity, 2013 - cell.com
Mononuclear phagocytes, including monocytes, macrophages, and dendritic cells,
contribute to tissue integrity as well as to innate and adaptive immune defense. Emerging …

Non-classical monocytes display inflammatory features: validation in sepsis and systemic lupus erythematous

R Mukherjee, P Kanti Barman, P Kumar Thatoi… - Scientific reports, 2015 - nature.com
Given the importance of monocytes in pathogenesis of infectious and other inflammatory
disorders, delineating functional and phenotypic characterization of monocyte subsets has …

Biological applications of magnetic nanoparticles

M Colombo, S Carregal-Romero, MF Casula… - Chemical Society …, 2012 - pubs.rsc.org
In this review an overview about biological applications of magnetic colloidal nanoparticles
will be given, which comprises their synthesis, characterization, and in vitro and in vivo …

Deciphering the transcriptional network of the dendritic cell lineage

JC Miller, BD Brown, T Shay, EL Gautier, V Jojic… - Nature …, 2012 - nature.com
Although much progress has been made in the understanding of the ontogeny and function
of dendritic cells (DCs), the transcriptional regulation of the lineage commitment and …

OsteoMacs: Key players around bone biomaterials

RJ Miron, DD Bosshardt - Biomaterials, 2016 - Elsevier
Osteal macrophages (OsteoMacs) are a special subtype of macrophage residing in bony
tissues. Interesting findings from basic research have pointed to their vast and substantial …

Single-cell transcriptome profiling of an adult human cell atlas of 15 major organs

S He, LH Wang, Y Liu, YQ Li, HT Chen, JH Xu, W Peng… - Genome biology, 2020 - Springer
Background As core units of organ tissues, cells of various types play their harmonious
rhythms to maintain the homeostasis of the human body. It is essential to identify the …

Therapeutic applications of macrophage colony-stimulating factor-1 (CSF-1) and antagonists of CSF-1 receptor (CSF-1R) signaling

DA Hume, KPA MacDonald - … Journal of the American Society of …, 2012 - ashpublications.org
Macrophage-colony stimulating factor (CSF-1) signaling through its receptor (CSF-1R)
promotes the differentiation of myeloid progenitors into heterogeneous populations of …