Cannabis sativa L. as a Natural Drug Meeting the Criteria of a Multitarget Approach to Treatment

A Stasiłowicz, A Tomala, I Podolak… - International journal of …, 2021 - mdpi.com
Cannabis sativa L. turned out to be a valuable source of chemical compounds of various
structures, showing pharmacological activity. The most important groups of compounds …

Cannabidiol and other non-psychoactive cannabinoids for prevention and treatment of gastrointestinal disorders: useful nutraceuticals?

V Martínez, A Iriondo De-Hond, F Borrelli… - International Journal of …, 2020 - mdpi.com
Cannabis sativa is an aromatic annual flowering plant with several botanical varieties, used
for different purposes, like the production of fibers, the production of oil from the seeds, and …

Cannabis, the Endocannabinoid System and Immunity—the Journey from the Bedside to the Bench and Back

O Almogi-Hazan, R Or - International journal of molecular sciences, 2020 - mdpi.com
The Cannabis plant contains numerous components, including cannabinoids and other
active molecules. The phyto-cannabinoid activity is mediated by the endocannabinoid …

Endocannabinoid system as a promising therapeutic target in inflammatory bowel disease–a systematic review

S Hryhorowicz, M Kaczmarek-Ryś, A Zielińska… - Frontiers in …, 2021 - frontiersin.org
Inflammatory bowel disease (IBD) is a general term used to describe a group of chronic
inflammatory conditions of the gastrointestinal tract of unknown etiology, including two …

Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer

M Grill, C Högenauer, A Blesl, J Haybaeck… - Scientific reports, 2019 - nature.com
Preclinical studies have demonstrated that the endocannabinoid system (ECS) plays an
important role in the protection against intestinal inflammation and colorectal cancer (CRC); …

Endocannabinoids inhibit the induction of virulence in enteric pathogens

M Ellermann, AR Pacheco, AG Jimenez, RM Russell… - Cell, 2020 - cell.com
Endocannabinoids are host-derived lipid hormones that fundamentally impact
gastrointestinal (GI) biology. The use of cannabis and other exocannabinoids as anecdotal …

Cannabinoids for treating inflammatory bowel diseases: where are we and where do we go?

C Hasenoehrl, M Storr, R Schicho - Expert review of …, 2017 - Taylor & Francis
Introduction: Fifty years after the discovery of Δ9-tetrahydrocannabinol (THC) as the
psychoactive component of Cannabis, we are assessing the possibility of translating this …

[HTML][HTML] The use of complementary and alternative medicine in patients with inflammatory bowel disease

SC Lin, AS Cheifetz - Gastroenterology & hepatology, 2018 - ncbi.nlm.nih.gov
Complementary and alternative medicine (CAM) includes products or medical practices that
encompass herbal and dietary supplements, probiotics, traditional Chinese medicines, and …

Alginate-based drug carrier systems to target inflammatory bowel disease: a review

D Swastha, N Varsha, S Aravind, KB Samyuktha… - International Journal of …, 2023 - Elsevier
Inflammatory bowel disease (IBD) is an inflammatory disorder that affects the gastrointestinal
tract. IBD has become an increasingly common condition in both developed and developing …

Carboxylesterase 2 proteins are efficient diglyceride and monoglyceride lipases possibly implicated in metabolic disease

G Chalhoub, S Kolleritsch, LK Maresch, U Taschler… - Journal of lipid …, 2021 - ASBMB
Abstract Carboxylesterase 2 (CES2/Ces2) proteins exert established roles in (pro) drug
metabolism. Recently, human and murine CES2/Ces2c have been discovered as …