In light of the clinical evidence implicating dopamine in schizophrenia and the prominent
hypotheses put forth regarding alterations in dopaminergic transmission in this disease …

Schizophrenia is a common and debilitating illness, characterized by chronic psychotic
symptoms and psychosocial impairment that exact considerable human and economic …

Context Current drug treatments for schizophrenia are inadequate for many patients, and
despite 5 decades of drug discovery, all of the treatments rely on the same mechanism …

The development of electrochemical recordings with small carbon‐fiber electrodes has
significantly advanced the understanding of the regulation of catecholamine transmission in …

Altered subcortical dopaminergic activity is thought to be involved in the pathophysiology of
several disorders including schizophrenia, substance abuse and attention deficit …

Identifying genes for bipolar mood disorders through classic genetics has proven difficult.
Here, we present a comprehensive convergent approach that translationally integrates brain …

Background: Striatal dopaminergic neurotransmission has been postulated to be
fundamental to the emergence of key symptoms of schizophrenia, such as psychotic …

This review gives an overview of those in vivo imaging studies on synaptic
neurotransmission, which so far have been performed on patients with mental and affective …

Antipsychotic drugs are effective interventions in schizophrenia. However, the efficacy of
these agents often decreases over time, which leads to treatment failure and symptom …

Parkinsonism in patients taking neuroleptic medications might be induced by dopamine
receptor blockade alone or by dopamine blockade with nigrostriatal dysfunction. The …