Macro-/micro-environment-sensitive chemosensing and biological imaging

Z Yang, J Cao, Y He, JH Yang, T Kim, X Peng… - Chemical Society …, 2014 - pubs.rsc.org
Environment-related parameters, including viscosity, polarity, temperature, hypoxia, and pH,
play pivotal roles in controlling the physical or chemical behaviors of local molecules. In …

Fluorescent probes for lipid rafts: from model membranes to living cells

AS Klymchenko, R Kreder - Chemistry & biology, 2014 - cell.com
Membrane microdomains (rafts) remain one of the controversial issues in biophysics.
Fluorescent molecular probes, which make these lipid nanostructures visible through optical …

Suppression of Kasha's rule as a mechanism for fluorescent molecular rotors and aggregation-induced emission

H Qian, ME Cousins, EH Horak, A Wakefield… - Nature …, 2017 - nature.com
Although there are some proposed explanations for aggregation-induced emission, a
phenomenon with applications that range from biosensors to organic light-emitting diodes …

The role of ultrasound-driven microbubble dynamics in drug delivery: from microbubble fundamentals to clinical translation

S Roovers, T Segers, G Lajoinie, J Deprez, M Versluis… - Langmuir, 2019 - ACS Publications
In the last couple of decades, ultrasound-driven microbubbles have proven excellent
candidates for local drug delivery applications. Besides being useful drug carriers …

Fluorescence lifetime imaging (FLIM): Basic concepts and some recent developments

K Suhling, LM Hirvonen, JA Levitt, PH Chung… - Medical photonics, 2015 - Elsevier
Fluorescence lifetime imaging (FLIM) is a key fluorescence microscopy technique to map the
environment and interaction of fluorescent probes. It can report on photophysical events that …

Fatty acid membrane assembly on coacervate microdroplets as a step towards a hybrid protocell model

TY Dora Tang, C Rohaida Che Hak, AJ Thompson… - Nature …, 2014 - nature.com
Mechanisms of prebiotic compartmentalization are central to providing insights into how
protocellular systems emerged on the early Earth. Protocell models are based …

Molecular rotors: fluorescent sensors for microviscosity and conformation of biomolecules

M Paez‐Perez, MK Kuimova - Angewandte Chemie, 2024 - Wiley Online Library
The viscosity and crowding of biological environment are considered vital for the correct
cellular function, and alterations in these parameters are known to underly a number of …

Micro‐bio‐chemo‐mechanical‐systems: Micromotors, microfluidics, and nanozymes for biomedical applications

J Mujtaba, J Liu, KK Dey, T Li, R Chakraborty… - Advanced …, 2021 - Wiley Online Library
Wireless nano‐/micromotors powered by chemical reactions and/or external fields generate
motive forces, perform tasks, and significantly extend short‐range dynamic responses of …

Synergistic effects of multiple rotors and hydrogen-bond interactions lead to sensitive near-infrared viscosity probes for live-cell microscopy

D Li, T Shen, X Xue, W Chen, W Tao, W Chi… - Science China …, 2023 - Springer
Abstract Changes in cellular viscosity are associated with various physiological processes
and pathological conditions. To study these cellular processes and functions, highly …

A molecular rotor for measuring viscosity in plasma membranes of live cells

I López-Duarte, TT Vu, MA Izquierdo, JA Bull… - Chemical …, 2014 - pubs.rsc.org
Molecular rotors have emerged as versatile probes for microscopic viscosity in live cells,
however, the exclusive localisation of rotors in the plasma membrane has remained elusive …