Pancreatic cancer is the world's fourth largest causative factor of mortality with a five year of
survival rate. Poor definitive diagnosis can be ascribed to both problematic early detections …

Globally, colorectal cancer is a major health problem that ranks in third place in terms of
occurrences and second in terms of mortality worldwide. New cases increase annually, with …

Introduction Delayed wound healing represents a common health hazard. Traditional herbal
products have been often utilized to promote wound contraction. The current study aimed at …

Piceatannol (PIC), a naturally occurring polyphenolic stilbene, has pleiotropic
pharmacological activities. It has reported cytotoxic activities against different cancer cells. In …

This work aimed at improving the targeting and cytotoxicity of simvastatin (SMV) against
colon cancer cells. SMV was encapsulated in chitosan polymers, followed by eudragit S100 …

As a hydroxymethylglutaryl coenzyme A (HMG-CoA) reductase inhibitor, Fluvastatin (FLV) is
used for reducing low-density lipoprotein (LDL) cholesterol as well as to prevent …

The aim of this study was to develop a novel self-nanoemulsifying drug delivery system
(SNEDDS) of brigatinib, a poorly soluble anticancer drug, so as to improve its solubility, in …

In the global incidence of peptic ulcer, with the associated rates of hospitalizations and
mortality are increasing, in the United States, peptic ulcer disease affects approximately 4.6 …

To improve the water solubility of thymoquinone (TQ), a major constituent of Nigella sativa
seed oil, a TQ-loaded self-nanoemulsifying drug delivery system (SNEDDS) was prepared …

Febuxostat (FBX) is used to treat gout and chronic hyperuricemia. However, its
bioavailability is moderate (49%) as a result of low solubility and first-pass metabolism …