Bacteriophage T4 is the most well-studied member of Myoviridae, the most complex family of
tailed phages. T4 assembly is divided into three independent pathways: the head, the tail …

Tailed bacteriophages use nanomotors, or molecular machines that convert chemical
energy into physical movement of molecules, to insert their double-stranded DNA genomes …

Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological
structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …

Bacteriophages have been a model system to study assembly processes for over half a
century. Formation of infectious phage particles involves specific protein-protein and protein …

Genome packaging is a fundamental process in a viral life cycle. Many viruses assemble
preformed capsids into which the genomic material is subsequently packaged. These …

Large dsDNA bacteriophages and herpesviruses encode a powerful ATP-driven DNA-
translocating machine that encapsidates a viral genome into a preformed capsid shell or …

The genome packaging motor of bacteriophages and herpesviruses is built by two
terminase subunits, known as large (TerL) and small (TerS), both essential for viral genome …

Tailed bacteriophages and herpesviruses assemble infectious particles via an empty
precursor capsid (or 'procapsid') built by multiple copies of coat and scaffolding protein and …

The bacteriophage T4 capsid is an elongated icosahedron, 120 nm long and 86 nm wide,
and is built with three essential proteins; gp23*, which forms the hexagonal capsid lattice …

Tailed DNA bacteriophages assemble empty procapsids that are subsequently filled with the
viral genome by means of a DNA packaging machine situated at a special fivefold vertex …