The role of PIP5K1A in cancer development and progression
M Yin, Y Wang - Medical Oncology, 2022 - Springer
Malignant tumors are formed via a pathological process of uncontrolled cell division that
seriously endangers human physical and mental health. The PI3K/AKT signaling pathway …
seriously endangers human physical and mental health. The PI3K/AKT signaling pathway …
In silico approaches for drug repurposing in oncology: a scoping review
BRR Cavalcante, RD Freitas… - Frontiers in …, 2024 - frontiersin.org
Introduction: Cancer refers to a group of diseases characterized by the uncontrolled growth
and spread of abnormal cells in the body. Due to its complexity, it has been hard to find an …
and spread of abnormal cells in the body. Due to its complexity, it has been hard to find an …
[HTML][HTML] Rupatadine inhibits colorectal cancer cell proliferation through the PIP5K1A/Akt/CDK2 pathway
L Jiang, Z Zhang, Z Luo, L Li, S Yuan, M Cui… - Biomedicine & …, 2024 - Elsevier
Abstract Background Phosphatidylinositol-4-phosphate 5-kinase type 1 alpha (PIP5K1A)
acts upstream of the Akt regulatory pathway and is abnormally expressed in many types of …
acts upstream of the Akt regulatory pathway and is abnormally expressed in many types of …
Kinetic analysis of the transphosphorylation with creatine kinase by pressure-assisted capillary electrophoresis/dynamic frontal analysis
M Mine, H Mizuguchi, T Takayanagi - Analytical and Bioanalytical …, 2021 - Springer
Kinetic reactions of the transphosphorylation with creatine kinase (CK) were individually
investigated between creatine (Cr) and creatine phosphate (CrP) by pressure-assisted …
investigated between creatine (Cr) and creatine phosphate (CrP) by pressure-assisted …
Autodisplay of human PIP5K1α lipid kinase on Escherichia coli and inhibitor testing
K Strätker, S Haidar, M Dubiel, A Estévez-Braun… - Enzyme and Microbial …, 2021 - Elsevier
Abstract The human phosphatidylinositol 4-phosphate 5-kinase type I α (hPIP5K1α) plays a
major role in the PI3K/AKT/mTOR signaling pathway. As it has been shown before that …
major role in the PI3K/AKT/mTOR signaling pathway. As it has been shown before that …
[HTML][HTML] 1, 2, 3-Triazole-totarol conjugates as potent PIP5K1α lipid kinase inhibitors
Abstract The human phosphatidylinositol 4-phosphate 5-kinase type I α (hPIP5K1α) plays a
key role in the development of prostate cancer. In this work, seventeen derivatives of the …
key role in the development of prostate cancer. In this work, seventeen derivatives of the …
[图书][B] Untersuchungen zur Interaktion des Proliferating Cell Nuclear Antigen (PCNA) mit p15 und Identifizierung eines potenten peptidischen Inhibitors
S Hardebeck - 2023 - search.proquest.com
Die PCNA-p15-Interaktion ist ein vielversprechendes Target für die Krebstherapie. Zur
Identifizierung peptidischer Inhibitoren dieser Interaktion wurde ein …
Identifizierung peptidischer Inhibitoren dieser Interaktion wurde ein …
The Role of the Central mTOR Signaling Pathway in Psoriasis Pathogenesis and Its Therapeutic Targeting with Fisetin
T Roy - 2022 - search.proquest.com
Psoriasis (PS) is a common chronic autoimmune skin disorder afflicting over 3% of the
population globally and is associated with significant comorbidities and reduced quality of …
population globally and is associated with significant comorbidities and reduced quality of …
[PDF][PDF] キャピラリー電気泳動/動的前端分析による酵素反応の速度論解析
峯大典 - (No Title), 2022 - repo.lib.tokushima-u.ac.jp
酵素とは触媒として働くタンパク質の総称であり, 生物における物質代謝やエネルギー代謝を円滑に
進めるために必要不可欠である [1]. 酵素の速度論解析は, 薬物代謝速度の予測 …
進めるために必要不可欠である [1]. 酵素の速度論解析は, 薬物代謝速度の予測 …